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Receptor, Melanocortin, Type 2

Known as: Receptor, MC2, Melanocortin 2 Receptor, Melanocortin Receptor 2 
A melanocortin receptor subtype found primarily in the ADRENAL CORTEX. It shows specificity for ADRENOCORTICOTROPIC HORMONE.
National Institutes of Health

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In BloodMC2R geneagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Analyzing the effects of co-expression of chick (Gallus gallus) melanocortin receptors with either chick MRAP1 or MRAP2 in CHO cells on sensitivity to ACTH(1-24) or ACTH(1-13)NH2: Implications for…
2015
2015
Structure/function studies on the activation of the rainbow trout melanocortin-2 receptor.
2014
2014
Analysis of the pharmacological properties of chicken melanocortin-2 receptor (cMC2R) and chicken melanocortin-2 accessory protein 1 (cMRAP1).
2012
2012
Identification of an MRAP-independent melanocortin-2 receptor: functional expression of the cartilaginous fish, Callorhinchus milii, melanocortin-2 receptor in CHO cells.
Phylogenetic analyses indicate that the genome of the cartilaginous fish, Callorhynchus milii (elephant shark), encodes a… 
Highly Cited
2011
Highly Cited
2011
ttenuation of the cortisol response to stress in female rainbow trout hronically exposed to dietary selenomethionine
Selenomethionine (Se-Met) is the major dietary form of selenium (Se). While Se is a required nutrient, it can also influence the… 
2011
2011
Melanocortin receptor subtypes in interrenal cells and corticotropic activity of α-melanocyte-stimulating hormones in barfin flounder, Verasper moseri.
Review
2010
Review
2010
Missense mutations in the melanocortin 2 receptor accessory protein that lead to late onset familial glucocorticoid deficiency type 2.
BACKGROUND Familial glucocorticoid deficiency (FGD) is an autosomal recessive disorder characterized by isolated glucocorticoid… 
2007
2007
Clinical and biological phenotype of a patient with familial glucocorticoid deficiency type 2 caused by a mutation of melanocortin 2 receptor accessory protein.
Familial glucocorticoid deficiency (FGD) is a rare inherited disorder which may be caused by mutations in the ACTH receptor… 
2007
2007
Structural insights into the role of the ACTH receptor cysteine residues on receptor function.
The ACTH receptor, also known as the melanocortin-2 receptor (MC2R), is critical for ACTH-mediated adrenal glucocorticoid release… 
2004
2004
ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans.
It has previously been suggested that ACTH and ACTH-related peptides may act as paracrine modulators of insulin secretion in the… 
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