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Rat Chondrosarcoma

Known as: Chondrosarcoma (RENI) 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Suppression of hyaluronan synthesis attenuates the tumorigenicity of low‐grade chondrosarcoma
Hyaluronan (HA) has been shown to play crucial roles in the tumorigenicity of malignant tumors. Chondrosarcoma, particularly when… 
2014
2014
CRISPR/Cas9 mediated generation of stable chondrocyte cell lines with targeted gene knockouts; analysis of an aggrecan knockout cell line.
2013
2013
Meclozine Facilitates Proliferation and Differentiation of Chondrocytes by Attenuating Abnormally Activated FGFR3 Signaling in Achondroplasia
Achondroplasia (ACH) is one of the most common skeletal dysplasias with short stature caused by gain-of-function mutations in… 
2009
2009
The transcription factor Lc‐Maf participates in Col27a1 regulation during chrondrocyte maturation
2005
2005
An inhibitor of the stretch-activated cation receptor exerts a potent effect on chondrocyte phenotype.
Rat chondrosarcoma (RCS) cells are unusual in that they display a stable chondrocyte phenotype in monolayer culture. This… 
2004
2004
Cell-type specific trafficking of expressed mutant COMP in a cell culture model for PSACH.
2003
2003
The establishment and characterization of an immortal cell line with a stable chondrocytic phenotype
A cell line was developed from the transplantable Swarm rat chondrosarcoma (RCS) and has been maintained in continuous monolayer… 
Highly Cited
1999
Highly Cited
1999
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway.
Several genetic forms of human dwarfism have been linked to activating mutations in FGF receptor 3, indicating that FGF signaling… 
Highly Cited
1996
Highly Cited
1996
An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes
The molecular mechanisms by which mesenchymal cells differentiate into chondrocytes are still poorly understood. We have used the… 
Highly Cited
1995
Highly Cited
1995
Use of a New Rat Chondrosarcoma Cell line to Delineate a 119-Base Pair Chondrocyte-specific Enhancer Element and to Define Active Promoter Segments in the Mouse Pro-α1(II) Collagen Gene (*)
We show that a new rat chondrosarcoma (RCS) cell line established in long-term culture from the Swarm tumor displayed a stable… 
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