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Rag1 Mouse

Known as: Rag1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The hypoxic expression of the glucose transporter RAG1 reveals the role of the bHLH transcription factor Sck1 as a novel hypoxic modulator in Kluyveromyces lactis.
Glucose is the preferred nutrient for most living cells and is also a signaling molecule that modulates several cellular… 
2009
2009
A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity.
2009
2009
Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis
The RAG proteins initiate V(D)J recombination by mediating synapsis and cleavage of two different antigen receptor gene segments… 
2008
2008
RAG-Heptamer Interaction in the Synaptic Complex Is a Crucial Biochemical Checkpoint for the 12/23 Recombination Rule*
In V(D)J recombination, the RAG1 and RAG2 protein complex cleaves the recombination signal sequences (RSSs), generating a hairpin… 
2007
2007
Biochemical and Folding Defects in a RAG1 Variant Associated with Omenn Syndrome1
The RAG1 and RAG2 proteins are required to assemble mature Ag receptor genes in developing lymphocytes. Hypomorphic mutations in… 
2007
2007
Requirements for DNA hairpin formation by RAG1/2
The rearrangement of antigen receptor genes is initiated by double-strand breaks catalyzed by the RAG1/2 complex at the junctions… 
2004
2004
Amino Acid Residues in RAG1 Responsible for the Interaction with RAG2 during the V(D)J Recombination Process*
The V(D)J recombinase, a complex of RAG1 and RAG2, carries out a gene rearrangement process that is required for the achievement… 
2003
2003
Catalytic RAG1 mutants obstruct V(D)J recombination in vitro and in vivo.
Highly Cited
1996
Highly Cited
1996
A zinc-binding domain involved in the dimerization of RAG1.
Recombination-activating gene 1 (RAG1), as well as RAG2, are the only lymphoid-specific genes required for V(D)J recombination… 
Highly Cited
1996
Highly Cited
1996
Regions of RAG1 protein critical for V(D)J recombination
The products of the recombination activating genes RAG1 and RAG2 are essential for activating V(D)J recombination, and thus are… 
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