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Raclopride

Known as: Benzamide, 3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl)-methyl)-2-hydroxy-6-methoxy-, Raclopride [Chemical/Ingredient] 
A substituted benzamide that has antipsychotic properties. It is a dopamine D2 receptor (see RECEPTORS, DOPAMINE D2) antagonist.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Pathological gambling is an impulse control disorder reported in association with dopamine agonists used to treat Parkinson's… Expand
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Highly Cited
2006
Highly Cited
2006
A small group of Parkinson's disease (PD) patients compulsively use dopaminergic drugs despite causing harmful social… Expand
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Review
2002
Review
2002
  • P. Seeman
  • Canadian journal of psychiatry. Revue canadienne…
  • 2002
  • Corpus ID: 14930109
Background: Al though the prin ci pal brain tar get that all an tipsy chotic drugs at tach to is the do pamine D2 re cep tor, tra… Expand
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Highly Cited
2000
Highly Cited
2000
Administration of the N-methyl-D-aspartate (NMDA) antagonist S-ketamine in normals produces a psychosis-like syndrome including… Expand
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Highly Cited
1999
Highly Cited
1999
The present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (DA… Expand
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Highly Cited
1998
Highly Cited
1998
Dopaminergic neurotransmission may be involved in learning, reinforcement of behaviour, attention, and sensorimotor integration… Expand
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Highly Cited
1997
Highly Cited
1997
A major line of evidence that supports the hypothesis of dopamine overactivity in schizophrenia is the psychomimetic potential of… Expand
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Highly Cited
1992
Highly Cited
1992
Equilibrium striatal: cerebellar 11C‐raclopride (RAC) uptake ratios reflect the density of striatal dopamine D2 binding sites… Expand
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Highly Cited
1986
Highly Cited
1986
D2 dopamine receptors in the putamen of living human subjects were characterized by using the selective, high-affinity D2… Expand
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Highly Cited
1985
Highly Cited
1985
The substituted benzamide drug raclopride, [((-)-(S)-3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl) methyl)-6-methoxy-salicylamide… Expand
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