Raclopride

Known as: Benzamide, 3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl)-methyl)-2-hydroxy-6-methoxy-, Raclopride [Chemical/Ingredient] 
A substituted benzamide that has antipsychotic properties. It is a dopamine D2 receptor (see RECEPTORS, DOPAMINE D2) antagonist.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Pathological gambling is an impulse control disorder reported in association with dopamine agonists used to treat Parkinson's… (More)
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Highly Cited
2000
Highly Cited
2000
Administration of the N-methyl-D-aspartate (NMDA) antagonist S-ketamine in normals produces a psychosis-like syndrome including… (More)
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Highly Cited
1999
Highly Cited
1999
Clozapine exerts superior clinical efficacy and markedly enhances cortical dopamine output compared with classical antipsychotic… (More)
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Highly Cited
1998
Highly Cited
1998
Dopaminergic neurotransmission may be involved in learning, reinforcement of behaviour, attention, and sensorimotor integration… (More)
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Highly Cited
1998
Highly Cited
1998
Subanesthetic doses of the noncompetitive N-methyl-D-aspartate (NMDA) antagonist ketamine exacerbate psychosis in schizophrenic… (More)
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Highly Cited
1997
Highly Cited
1997
A major line of evidence that supports the hypothesis of dopamine overactivity in schizophrenia is the psychomimetic potential of… (More)
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Highly Cited
1993
Highly Cited
1993
Bilateral decreases in striatal 11C-raclopride binding were observed in adult female baboons with high resolution PET following… (More)
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Highly Cited
1993
Highly Cited
1993
Carbon-11-raclopride has been successfully utilized with PET to assess changes in endogenous dopamine concentration after… (More)
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Highly Cited
1992
Highly Cited
1992
Extensive neuroanatomical, neurophysiological, and behavioral evidence demonstrates that GABAergic neurons inhibit endogenous… (More)
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Highly Cited
1985
Highly Cited
1985
The substituted benzamide drug raclopride, [((-)-(S)-3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl) methyl)-6-methoxy-salicylamide… (More)
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