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Rab geranylgeranyltransferase

Known as: Rab GG transferase, Rab geranylgeranyl transferase 
National Institutes of Health

Related topics

Related topics

2 relations
CHM geneRABGGTA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Posttranslational modifications of Rab GTPases help their insertion into membranes
GTPases of the Rab family, which comprises more than 60 members in mammals, have emerged as key regulators of virtually all… 
Highly Cited
2010
Highly Cited
2010
Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2…
3-(3-Pyridyl)-2-hydroxy-2-phosphonopropanoic acid (3-PEHPC, 1) is a phosphonocarboxylate (PC) analogue of 2-(3-pyridyl)-1… 
2009
2009
Design, synthesis, and characterization of peptide-based rab geranylgeranyl transferase inhibitors.
Rab geranylgeranyl transferase (RabGGTase) catalyzes the attachment of geranylgeranyl isoprenoids to Rab guanine triphosphatases… 
Highly Cited
2007
Highly Cited
2007
Synthesis and Biological Evaluation of α-Halogenated Bisphosphonate and Phosphonocarboxylate Analogues of Risedronate
α-Halogenated analogues of the anti-resorptive bisphosphonate risedronate (5, Ris) and its phosphonocarboxylate cognate (7, 3… 
2007
2007
Synthesis of a fluorescent analogue of geranylgeranyl pyrophosphate and its use in a high-throughput fluorometric assay for Rab geranylgeranyltransferase
Protein prenylation is one of the most common post-translational modifications affecting hundreds of eukaryotic proteins. Rab… 
2005
2005
A specific feature of the angiosperm Rab escort protein (REP) and evolution of the REP/GDI superfamily.
2002
2002
Interaction of yeast Rab geranylgeranyl transferase with its protein and lipid substrates.
Small GTPases from the Rab/Ypt family regulate events of vesicular traffic in eukaryotic cells. For their activity, Rab proteins… 
2000
2000
Semi‐synthetic Rab proteins as tools for studying intermolecular interactions
Highly Cited
1996
Highly Cited
1996
Tomato Rab1A Homologs as Molecular Tools for Studying Rab Geranylgeranyl Transferase in Plant Cells
Rab proteins attach to membranes along the secretory pathway where they contribute to distinct steps in vesicle-mediated… 
1996
1996
Specific Prenylation of Tomato Rab Proteins by Geranylgeranyl Type-II Transferase Requires a Conserved Cysteine-Cysteine Motif
Posttranslational isoprenylation of some small GTP-binding proteins is required for their biological activity. Rab geranylgeranyl… 
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