RXDX-101

 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
RTK plays important roles in many cellular signaling processes involved in cancer growth and development. ALK, TRKA, TRKB, TRKC… (More)
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2017
2017
BACKGROUND Astrocytomas are the most common primary human brain tumors. Receptor tyrosine kinases (RTKs), including tyrosine… (More)
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2017
2017
Neurotrophic tyrosine kinase genes encode for the Trk-family proteins TrkA, TrkB, and TrkC, which have an important role in the… (More)
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Review
2016
Review
2016
Crizotinib is an oral inhibitor of anaplastic lymphoma kinase (ALK) with remarkable clinical activity in patients suffering from… (More)
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2016
2016
Neuroblastoma (NB) is one of the most common and deadly childhood solid tumors. These tumors are characterized by clinical… (More)
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2015
2015
1Niguarda Cancer Center, Ospedale Niguarda Ca' Granda, and Università degli Studi di Milano, Milan, Italy; 2Memorial Sloan… (More)
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2015
2015
INTRODUCTION Chromosomal rearrangements involving neurotrophic tyrosine kinase 1 (NTRK1) occur in a subset of non-small cell lung… (More)
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2014
2014
The Trk family of kinases, which include TrkA, TrkB and TrkC, are high affinity receptors for the neurotrophin family of nerve… (More)
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