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- Publications
- Influence
Classification of Bacillus and Brevibacillus species using rapid analysis of lipids by mass spectrometry
- Najla Almasoud, Y. Xu, +7 authors R. Goodacre
- Chemistry, Medicine
- Analytical and Bioanalytical Chemistry
- 7 September 2016
AbstractBacillus are aerobic spore-forming bacteria that are known to lead to specific diseases, such as anthrax and food poisoning. This study focuses on the characterization of these bacteria by… Expand
Validated LC-MS/MS assay for quantification of the newly approved tyrosine kinase inhibitor, dacomitinib, and application to investigating its metabolic stability
- A. S. Abdelhameed, A. Kadi, M. Attwa, H. Alrabiah
- Chemistry, Medicine
- PloS one
- 4 April 2019
Dacomitinib (DMB) is a second-generation irreversible tyrosine kinase inhibitor (TKI) that is claimed to overcome the disadvantages of the resistance reported for first-line epidermal growth factor… Expand
Charge-transfer complexes of cefpodoxime proxetil with chloranilic acid and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone: Experimental and theoretical studies
- Ola R Shehab, H. Alrabiah, H. A. Abdel-Aziz, G. Mostafa
- Chemistry
- 1 May 2018
Abstract Two new charge transfer complexes of cefpodoxime proxetil (CEP) as electron donor and chloranilic acid (CHA) or 2, 3-dichloro 5, 6-dicyano 1, 4-benzoquinone (DDQ) as acceptors have been… Expand
Molecular structure, vibrational spectra, NBO, Fukui function, HOMO-LUMO analysis and molecular docking study of 6-[(2-methylphenyl)sulfanyl]-5-propylpyrimidine-2,4(1H,3H)-dione
- H. Alrabiah, S. Muthu, +4 authors A. El-Emam
- Chemistry
- 25 May 2017
Theoretical and experimental FT-IR and FT-Raman vibrational spectral analysis of 6-[(2-methylphenyl)sulfanyl]-5-propylpyrimidine-2,4(1 H ,3 H )-dione have been recorded in the region 4000-400 cm -1… Expand
Chapter Six – Propranolol
- A. Al-majed, A. Bakheit, H. Aziz, F. Alajmi, H. Alrabiah
- Chemistry
- 2017
Propranolol is a noncardioselective β-blocker. It is reported to have membrane-stabilizing properties, but it does not own intrinsic sympathomimetic activity. Propranolol hydrochloride is used to… Expand
Metabolic Profiling of Geobacter sulfurreducens during Industrial Bioprocess Scale-Up
- H. Muhamadali, Y. Xu, +6 authors R. Goodacre
- Biology, Medicine
- Applied and Environmental Microbiology
- 6 March 2015
ABSTRACT During the industrial scale-up of bioprocesses it is important to establish that the biological system has not changed significantly when moving from small laboratory-scale shake flasks or… Expand
Molecular interactions of AL3818 (anlotinib) to human serum albumin as revealed by spectroscopic and molecular docking studies
- A. S. Abdelhameed, A. Bakheit, H. Alrabiah, Eman S. G. Hassan, Fahad M. Almutairi
- Chemistry
- 2019
Abstract Anlotinib (ANB) is a novel member of the tyrosine kinase inhibitors approved for different types of cancer, its binding to human serum albumin (HSA) is of significant pharmacological… Expand
High-throughput phenotyping of uropathogenic E. coli isolates with Fourier transform infrared spectroscopy.
- H. Alrabiah, E. Correa, M. Upton, R. Goodacre
- Chemistry, Medicine
- The Analyst
- 4 February 2013
Fourier transform infrared (FT-IR) spectroscopy is an established rapid whole-organism fingerprinting method that generates metabolic fingerprints from bacteria that reflect the phenotype of the… Expand
Multiple metabolomics of uropathogenic E. coli reveal different information content in terms of metabolic potential compared to virulence factors.
- H. Alrabiah, Y. Xu, +6 authors R. Goodacre
- Chemistry, Medicine
- The Analyst
- 28 July 2014
No single analytical method can cover the whole metabolome and the choice of which platform to use may inadvertently introduce chemical selectivity. In order to investigate this we analysed a… Expand
Implementation of Fourier transform infrared spectroscopy for the rapid typing of uropathogenic Escherichia coli
- S. Dawson, T. Gibreel, +4 authors M. Upton
- Biology, Medicine
- European Journal of Clinical Microbiology…
- 8 January 2014
In this paper, we demonstrate that Fourier transform infrared (FT-IR) spectroscopy is able to discriminate rapidly between uropathogenic Escherichia coli (UPEC) of key lineages with only relatively… Expand
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