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RWJ 22108

Known as: RWJ-22108 
National Institutes of Health

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Pyridines

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1998
1998
Design and discovery of RWJ 22108--a novel bronchoselective calcium channel blocker.
A series of cyclic sulfone dihydropyridines ranging in sulfone ring size from five to nine membered have been evaluated for… 
1997
1997
Inhibition of voltage-dependent Ca2+ channels of porcine tracheal smooth muscle by the novel Ca2+ channel antagonist RWJ-22108.
1993
1993
Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker.
RWJ 22108 (N-benzyl-N-methylaminoethyl 9-(2-chloro-6-fluorophenyl)-2,3,4,5,6,9-hexahydro-7-methyl-1, 1-dioxothiacyclohepteno-[3,2… 
1993
1993
Synthesis and biological properties of RWJ 22108, a bronchoselective calcium channel blocker.
The synthesis, biochemical and in vivo profile of RWJ 22108, an antiasthamtic cyclic sulfone dihydropyridine calcium channel… 
1993
1993
RWJ-22108 — a novel airway tissue — selective calcium channel blocker
RWJ-22108 is a novel calcium entry blocker that has potential therapeutic use as an antiasthmatic agent. Although displaying… 
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