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Calcific aortic valve disease (CAVD) is a progressive disorder that increases in prevalence with age. An important role in aortic… Expand The osteogenic transcription factor, Runx2, is abnormally expressed in prostate cancer (PCa) and associated with metastatic… Expand Background: RUNX2 is indispensable for mature osteoblast differentiation and function. Results: During osteogenic differentiation… Expand Runt‐related transcription factor 2 (RUNX2) belongs to the RUNX family of heterodimeric transcription factors, and is mainly… Expand Indian hedgehog (Ihh) is indispensable for osteoblast differentiation during embryonic development of the endochondral skeleton… Expand Mesenchymal stem cell commitment to an osteoprogenitor lineage requires the activity of Runx2, a molecule implicated in the… Expand Estrogen receptor-related receptor γ (ERRγ/ERR3/NR3B3) is a member of the orphan nuclear receptor with important functions in… Expand Runx2 is a bone-specific transcription factor that plays a critical role in bone development, postnatal bone formation, and… Expand Runx2-Cbfa1, a Runt transcription factor, plays important roles during skeletal development. It is required for differentiation… Expand