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Essentials RAS proteins are expressed in platelets but their functions are largely uncharacterized. TC21/RRas2 is required for… Expand AIM
To determine the functional significance of TC21 in esophageal squamous cell carcinoma (ESCC).
TC21 siRNA… Expand 560 Background: Several molecular factors have been associated with the sensitivity of breast cancers to tamoxifen (T). Pax2 can… Expand BACKGROUND
In search of novel molecular markers for oral cancer, we reported increased levels of TC21/R-Ras2 transcripts in oral… Expand Objectives: Early detection of esophageal cancer is hampered by paucity of molecular markers for diagnosis of this aggressive… Expand The signaling pathways of TC21-mediated transformation and cell survival are not well-established. In this study, we have… Expand ABSTRACT TC21 is a member of the Ras superfamily of small GTP-binding proteins that, like Ras, has been implicated in the… Expand Constitutively activated mutants of the Ras-related protein TC21/R-Ras2 cause tumorigenic transformation of NIH3T3 cells. However… Expand TC21 is a member of the Ras superfamily of small GTP‐binding proteins and, like Ras, has been implicated in the regulation of… Expand Although experimental studies suggest that aberrant Ras function can promote the malignant progression of human breast epithelial… Expand