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RRAS2 wt Allele

Known as: Related RAS Viral (r-ras) Oncogene Homolog 2 wt Allele, TC21 
Human RRAS2 wild-type allele is located in the vicinity of 11p15.2 and is approximately 80 kb in length. This allele, which encodes Ras-related… 
National Institutes of Health

Papers overview

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2018
2018
Essentials RAS proteins are expressed in platelets but their functions are largely uncharacterized. TC21/RRas2 is required for… 
2012
2012
AIM To determine the functional significance of TC21 in esophageal squamous cell carcinoma (ESCC). METHODS TC21 siRNA… 
2011
2011
560 Background: Several molecular factors have been associated with the sensitivity of breast cancers to tamoxifen (T). Pax2 can… 
2010
2010
BACKGROUND In search of novel molecular markers for oral cancer, we reported increased levels of TC21/R-Ras2 transcripts in oral… 
2005
2005
Objectives: Early detection of esophageal cancer is hampered by paucity of molecular markers for diagnosis of this aggressive… 
Highly Cited
2002
Highly Cited
2002
The signaling pathways of TC21-mediated transformation and cell survival are not well-established. In this study, we have… 
Highly Cited
1999
Highly Cited
1999
TC21 is a member of the Ras superfamily of small GTP‐binding proteins and, like Ras, has been implicated in the regulation of… 
Highly Cited
1999
Highly Cited
1999
Constitutively activated mutants of the Ras-related protein TC21/R-Ras2 cause tumorigenic transformation of NIH3T3 cells. However… 
Highly Cited
1996
Highly Cited
1996
Although experimental studies suggest that aberrant Ras function can promote the malignant progression of human breast epithelial…