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RPR 120844
Known as:
RPR-120844
, RPR120844
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (3)
Factor Xa inhibitors
Sulfonamides
Thiophenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.
W. R. Ewing
,
M. Becker
,
+21 authors
V. Chu
Journal of Medicinal Chemistry
1999
Corpus ID: 24796057
The discovery of a series of non-peptide factor Xa (FXa) inhibitors incorporating 3-(S)-amino-2-pyrrolidinone as a central…
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1999
1999
Sulfonamidopyrrolidinone factor Xa inhibitors: potency and selectivity enhancements via P-1 and P-4 optimization.
Y. M. Choi-Sledeski
,
D. Mcgarry
,
+20 authors
H. Pauls
Journal of Medicinal Chemistry
1999
Corpus ID: 25994705
Sulfonamidopyrrolidinones were previously disclosed as a selective class of factor Xa (fXa) inhibitors, culminating in the…
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1999
1999
RPR120844, a Novel, Specific Inhibitor of Coagulation Factor Xa Inhibits Venous Thrombosis in the Rabbit
J. Bostwick
,
R. Bentley
,
+8 authors
R. Leadley
Thrombosis and Haemostasis
1999
Corpus ID: 34911568
Summary The in vivo antithrombotic activity of RPR120844, a novel synthetic coagulation factor Xa (fXa) inhibitor (Ki = 7 nM…
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