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RP 40749

Known as: 2-Thiophenecarbothioamide, tetrahydro-N-methyl-2-(2-pyridinyl)-, 40749 RP, RP-40749 
National Institutes of Health

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Thiophenes

Papers overview

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2004
2004
Effect of 40749 RP on basal and sham feeding stimulated gastric secretion in man
Summary40749 RP, a pyridyl-2-tetrahydrothiophene derivative, is known to be a potent inhibitor of the gastric acid response to… 
1986
1986
Effects of single daily doses of a pyridil-2-tetrahydrothiophene derivative (40749 RP) on 24 hour H+ activity, nocturnal acid output, gastrin and pepsinogen I profiles in duodenal ulcer patients.
40749 RP is a pyridil-2-tetrahydrothiophene derivative, belonging to a new class of gastric antisecretory drugs. We compared its… 
1986
1986
[Treatment of gastric acid hypersecretion in the Zollinger-Ellison syndrome with a thioamide derivative (40749 RP). Comparison with ranitidine].
The efficacy of a new gastric antisecretory drug, 40749 RP, was studied in five cases of Zollinger-Ellison syndrome. Daily oral… 
1986
1986
Acute and chronic 24-hour gastric pH and pharmacokinetic studies with a long acting antisecretory drug (40749 RP) in peptic ulcer.
The purpose of this work was to compare the effects of a long acting antisecretory drug on 24-h gastric acidity after acute and… 
1985
1985
Influence of RP 40749 on basal and meal-stimulated serum-gastrin, serum-pepsinogen I, and gastrin-content of the antral mucosa in duodenal ulcer patients
Eighteen patients with active duodenal ulcer were treated with a novel antisecretory drug, RP 40749, either 100 mg or 150 mg as a… 
1984
1984
[Inhibition by a 2-pyridyltetrahydrothiophene derivative (40749 RP) of gastric secretion stimulated by pentagastrin. Results in 30 duodenal ulcer patients].
The aim of this study was to investigate the effects of a new antisecretory compound (40749 RP) on the pentagastrin stimulated… 
1983
1983
Effects of 40749 RP upon basal and pentagastrin-stimulated gastric secretion in man
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