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RO5424802

Known as: ALK Inhibitor RO5424802 
An orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity. Upon administration, ALK… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
7610 (2010). 43. Lee, J.O. et al. Anaplastic lymphoma kinase translocation: a predictive biomarker of pemetrexed in patients with… Expand
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2014
2014
TO THEEDITOR:Intheircost-effectivenessanalysisof ALKtesting and crizotinib treatment, Djalalov et al 1 put a price tag on this… Expand
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Review
2014
Review
2014
The last decade has witnessed the development of oncogene-directed targeted therapies that have significantly changed the… Expand
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Review
2014
Review
2014
The rate of the anaplastic lymphoma kinase (ALK) gene rearrangements in non-small cell lung cancer (NSCLC) tissues is 3%-5%. The… Expand
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Currently, crizotinib is the only drug that has been approved for treatment of ALK-rearranged non-small-cell lung… Expand
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