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RO5323441
Known as:
Anti-PGF Monoclonal Antibody RO5323441
A humanized IgG1 monoclonal antibody directed against the placenta growth factor (PGF), with potential anti-angiogenic and antineoplastic activities…
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National Institutes of Health
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Related topics
Related topics
1 relation
antigen binding
Papers overview
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2017
2017
An apparent clinical pharmacokinetic drug–drug interaction between bevacizumab and the anti-placental growth factor monoclonal antibody RO5323441 via a target-trapping mechanism
Ka Wang
,
F. S. Stark
,
+8 authors
O. Krieter
Cancer Chemotherapy and Pharmacology
2017
Corpus ID: 33914409
PurposeRO5323441 is a humanized anti-placental growth factor (PlGF) monoclonal antibody that has shown preclinical activity in…
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2013
2013
Placental Growth Factor (PlGF)–Specific Uptake in Tumor Microenvironment of 89Zr-Labeled PlGF Antibody RO5323441
T. O. Oude Munnink
,
K. Tamas
,
+7 authors
E. de Vries
Journal of Nuclear Medicine
2013
Corpus ID: 2789644
Placental growth factor (PlGF) is a member of the proangiogenic vascular endothelial growth factor family, which is upregulated…
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2013
2013
Phase I study of anti-PlGF monoclonal antibody (mAb) RO5323441 (RO) and anti-VEGF mab bevacizumab (BV) in patients with recurrent glioblastoma (GBM).
U. Lassen
,
O. Chinot
,
+11 authors
M. Weller
2013
Corpus ID: 79382989
2092 Background: BV inhibits VEGF and is approved for progressive GBM following prior therapy. The placental growth factor (PlGF…
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2013
2013
Placental Growth Factor ( PlGF ) – Specific Uptake in Tumor Microenvironment of 89 Zr-Labeled PlGF Antibody RO 5323441
T. O. Munnink
,
K. Tamas
,
+7 authors
E. Vries
2013
Corpus ID: 13556380
1Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands…
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2010
2010
Abstract 1370: RO5323441, a humanized monoclonal antibody against the placenta growth factor, blocks PlGF-induced VEGFR-1 phosphorylation in vitro and tumor growth in vivo
C. Rizzo
,
Xuefeng Yin
,
+6 authors
M. Simcox
2010
Corpus ID: 72439020
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Solid tumor growth requires new blood vessel…
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