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RO 3306

Known as: RO-3306, RO3306 
National Institutes of Health

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2 relations

Broader (2)

QuinolinesThiazoles

Papers overview

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2017
2017
Cis-trimethoxy resveratrol induces intrinsic apoptosis via prometaphase arrest and prolonged CDK1 activation pathway in human Jurkat T cells
Cis-trimethoxy resveratrol (cis-3M-RES) induced dose-dependent cytotoxicity and apoptotic DNA fragmentation in Jurkat T cell… 
2016
2016
Flexibility vs. robustness in cell cycle regulation of timing of M-phase entry in Xenopus laevis embryo cell-free extract.
During the cell cycle, cyclin dependent kinase 1 (CDK1) and protein phosphatase 2A (PP2A) play major roles in the regulation of… 
2015
2015
Suppression of homologous recombination sensitizes human tumor cells to IGF‐1R inhibition
Inhibition of type 1 IGF receptor (IGF‐1R) sensitizes to DNA‐damaging cancer treatments, and delays repair of DNA double strand… 
2014
2014
Are Orai1 and Orai3 channels more important than calcium influx for cell proliferation?
2014
2014
Potentially Lethal Damage Repair in Drug Arrested G2-Phase Cells after Radiation Exposure
Potentially lethal damage (PLD) repair has been defined as that property conferring the ability of cells to recover from DNA… 
2014
2014
Cyclin-dependent kinase 1 inhibitor RO3306 promotes mitotic slippage in paclitaxel-treated HepG2 cells.
Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm and current systemic chemotherapy are mostly ineffective… 
2014
2014
The Cooperation Effect of RO3306 and AZD2281 in the Treatment of BRCA1WT Breast Cancer in vitro
Objective To investigate whether reduced CDK1 activity can sensitize BRCA1-proficient(BRCA1WT)tumor cells to PARP1 inhibi-tion… 
2013
2013
Cyclin-dependent kinase 1 inhibitor RO3306 promotes mitotic slippage in paclitaxel-treated HepG2 cells.
Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm and current systemic chemotherapy are mostly ineffective… 
2012
2012
Inducing “cytokinesis” without mitosis in unfertilized Drosophila eggs
Selection of the cleavage plane during cytokinesis in dividing cells is linked to the position of the mitotic spindle. A major… 
2010
2010
A new role for Cdks in the DNA damage response
Comment on: Alvarez-Fernández M, et al. EMBO Rep 2010; 11:452-8. 
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