RNF8 gene

Known as: KIAA0646, RING FINGER PROTEIN 8, RNF8 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2018
0102020012018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Mitotic cells inactivate DNA double-strand break (DSB) repair, but the rationale behind this suppression remains unknown. Here… (More)
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Highly Cited
2012
Highly Cited
2012
In response to DNA damage, cells initiate complex signalling cascades leading to growth arrest and DNA repair. The recruitment of… (More)
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Highly Cited
2012
Highly Cited
2012
The ubiquitination cascade has a key role in the assembly of repair and signaling proteins at sites of double-strand DNA breaks… (More)
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Highly Cited
2009
Highly Cited
2009
DNA double strand breaks (DSBs) initiate reversible cellular checkpoint and repair activities. Whereas many of the activating… (More)
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Highly Cited
2009
Highly Cited
2009
Chromatin modifications are an important component of the of DNA damage response (DDR) network that safeguard genomic integrity… (More)
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2008
2008
The ubiquitination of PCNA is an essential event in the operation of the DNA Damage Tolerance (DDT) pathway that is activated… (More)
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Highly Cited
2007
Highly Cited
2007
Cells respond to DNA double-strand breaks by recruiting factors such as the DNA-damage mediator protein MDC1, the p53-binding… (More)
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Highly Cited
2007
Highly Cited
2007
Accumulation of repair proteins on damaged chromosomes is required to restore genomic integrity. However, the mechanisms of… (More)
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Highly Cited
2007
Highly Cited
2007
DNA-damage signaling utilizes a multitude of posttranslational modifiers as molecular switches to regulate cell-cycle checkpoints… (More)
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Highly Cited
2006
Highly Cited
2006
The heterodimeric ubiquitin conjugating enzyme (E2) UBC13-UEV mediates polyubiquitylation through lysine 63 of ubiquitin (K63… (More)
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