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RNA Cleavage

Known as: Cleavage, RNA, Cleavages, RNA, RNA Cleavages 
A reaction that severs one of the sugar-phosphate linkages of the phosphodiester backbone of RNA. It is catalyzed enzymatically, chemically, or by… 
National Institutes of Health

Related topics

Related topics

4 relations
Nonsense Mediated mRNA DecayRNA Splicingaspects of radiation effectsphysiological aspects

Papers overview

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2009
2009
Human cytosolic tRNase ZL can downregulate gene expression through miRNA
2005
2005
Uridine binding by Zn(II) macrocyclic complexes: diversion of RNA cleavage catalysts.
Zn(II) complexes of 1-oxa-4,7,10-triazacyclododecane (12[ane]N3O), 1,5,9-triazacyclododecane (12[ane]N3), and 1-hydroxyethyl-1,4… 
2001
2001
Enhancing sequence-specific cleavage of RNA within a duplex region: incorporation of 1,3-propanediol linkers into oligonucleotide conjugates of serinol-terpyridine.
The syntheses and RNA cleavage efficiencies of a new series of oligonucleotide conjugates of Cu(II)-serinol-terpyridine and 1,3… 
Highly Cited
2000
Highly Cited
2000
The N-Terminal Domain That Distinguishes Yeast from Bacterial RNase III Contains a Dimerization Signal Required for Efficient Double-Stranded RNA Cleavage
ABSTRACT Yeast Rnt1 is a member of the double-stranded RNA (dsRNA)-specific RNase III family identified by conserved dsRNA… 
1999
1999
Probing Ribosome Structure by Europium-Induced RNA Cleavage
Abstract Divalent metal ions are absolutely required for the structure and catalytic activities of ribosomes. They are partly… 
1998
1998
Specific inhibition of influenza virus RNA polymerase and nucleoprotein gene expression by circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligonucleotides
1997
1997
Role of Nd3+ and Pb2+ on the RNA cleavage reaction by a small ribozyme.
Leadzyme is a ribozyme that requires Pb2+. We have previously shown that the addition of Nd3+ in the presence of Pb2+ increased… 
Highly Cited
1996
Highly Cited
1996
Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure.
The hairpin ribozyme is a small self-cleaving RNA that can be engineered for RNA cleavage in trans and has potential as a… 
Highly Cited
1992
Highly Cited
1992
Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structures.
One of the inherent problems in the use of antisense oligodeoxynucleotides to ablate gene expression in cell cultures is that the… 
1979
1979
Total synthesis of a tyrosine suppressor transfer RNA gene. XVII. Transcription, in vitro, of the synthetic gene and processing of the primary transcript to transfer RNA.
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