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RMI1 gene

Known as: BLM-ASSOCIATED PROTEIN, 75-KD, RMI1, C9ORF76 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Pervasive and essential roles of the Top3-Rmi1 decatenase orchestrate recombination and facilitate chromosome segregation in meiosis.
The Bloom's helicase ortholog, Sgs1, plays central roles to coordinate the formation and resolution of joint molecule… Expand
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Highly Cited
2012
Highly Cited
2012
Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.
Genetic evidence indicates that Saccharomyces cerevisiae Sgs1, Top3, and Rmi1 resolve topologically linked intermediates arising… Expand
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Highly Cited
2011
Highly Cited
2011
Pathways for Holliday Junction Processing during Homologous Recombination in Saccharomyces cerevisiae
ABSTRACT The Saccharomyces cerevisiae Rmi1 protein is a component of the highly conserved Sgs1-Top3-Rmi1 complex. Deletion of… Expand
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Highly Cited
2010
Highly Cited
2010
Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1–Top3
A double Holliday junction (dHJ) is a central intermediate of homologous recombination that can be processed to yield crossover… Expand
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Highly Cited
2010
Highly Cited
2010
Human Topoisomerase IIIα Is a Single-stranded DNA Decatenase That Is Stimulated by BLM and RMI1*
Human topoisomerase IIIα is a type IA DNA topoisomerase that functions with BLM and RMI1 to resolve DNA replication and… Expand
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Review
2007
Review
2007
The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'?
RecQ helicases, together with topoisomerase III and Rmi1 family proteins, form an evolutionarily conserved complex that is… Expand
Highly Cited
2006
Highly Cited
2006
A Double Holliday Junction Dissolvasome Comprising BLM, Topoisomerase IIIα, and BLAP75*
Bloom syndrome (BS), an autosomal recessive disorder, is marked by a high incidence of cancer early in life. Cells derived from… Expand
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Highly Cited
2005
Highly Cited
2005
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity
Bloom's syndrome (BS) is a rare human genetic disorder characterized by dwarfism, immunodeficiency, genomic instability and… Expand
Highly Cited
2005
Highly Cited
2005
RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex
SGS1 encodes a DNA helicase whose homologues in human cells include the BLM, WRN, and RECQ4 genes, mutations in which lead to… Expand
Highly Cited
2005
Highly Cited
2005
Yeast Rmi1/Nce4 Controls Genome Stability as a Subunit of the Sgs1-Top3 Complex
ABSTRACT Genome stability requires a set of RecQ-Top3 DNA helicase-topoisomerase complexes whose sole budding yeast homolog is… Expand
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