RIPK1 wt Allele

Known as: FLJ39204, Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1 wt Allele, RIP 
Human RIPK1 wild-type allele is located in the vicinity of 6p25.2 and is approximately 37 kb in length. This allele, which encodes receptor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
02419992017

Papers overview

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2017
2017
RIP1 is an essential regulator of TNF-induced signaling complexes mediating NF-κB activation, apoptosis and necroptosis. Loss of… (More)
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Highly Cited
2012
Highly Cited
2012
Inhibitor of apoptosis (IAP) proteins cIAP1, cIAP2, and XIAP (X-linked IAP) regulate apoptosis and cytokine receptor signalling… (More)
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Highly Cited
2011
Highly Cited
2011
In multiple tumor types, activation of the transcription factor NF-κB increases the resistance of tumor cells to anticancer… (More)
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2009
2009
Smac mimetic compounds (SMC) are novel small molecules being developed for cancer therapy. The mechanism of SMC-induced… (More)
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Highly Cited
2006
Highly Cited
2006
Stimulation of cells with tumor necrosis factor (TNFalpha) triggers a recruitment of various signaling molecules, such as RIP, to… (More)
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Highly Cited
2005
Highly Cited
2005
Rip1 is required for IkappaB kinase activation in response to tumor necrosis factor alpha (TNF-alpha) and has been implicated in… (More)
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2005
2005
Nuclear factor-kappaB (NF-kappaB) is the main target of anti-inflammatory therapies in human chronic inflammatory bowel diseases… (More)
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2004
Highly Cited
2004
Ulcerative colitis and Crohn's disease are the two entities of chronic inflammatory bowel diseases (IBD). One of the main… (More)
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2003
2003
The death-domain kinase RIP (receptor-interacting protein) is an important effector of tumour necrosis factor (TNF) signalling… (More)
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1999
1999
The tumor necrosis factor receptor 1 (TNFR1) and the Fas receptor recruit complexes formed by the interactions between RIP kinase… (More)
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