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RHOT1 gene

Known as: RAS HOMOLOG GENE FAMILY, MEMBER T1, ras homolog family member T1, FLJ11040 
National Institutes of Health

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1 relation

Broader (1)

Genes

Papers overview

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Highly Cited
2018
Highly Cited
2018
α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies
Significance α-Synuclein (α-Syn) aggregation underlies neurodegeneration in synucleinopathies. However, the nature of α-Syn… 
Highly Cited
2018
Highly Cited
2018
MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress.
Highly Cited
2018
Highly Cited
2018
Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX
ABSTRACT Mitochondrial distribution in cells is critical for cellular function and proper inheritance during cell division. In… 
2016
2016
Structural insights into Parkin substrate lysine targeting from minimal Miro substrates
Hereditary Parkinson’s disease is commonly caused by mutations in the protein kinase PINK1 or the E3 ubiquitin ligase Parkin… 
Highly Cited
2015
Highly Cited
2015
Reciprocal Regulation of Mitochondrial Dynamics and Calcium Signaling in Astrocyte Processes
We recently showed that inhibition of neuronal activity, glutamate uptake, or reversed-Na+/Ca2+-exchange with TTX, TFB-TBOA, or… 
Highly Cited
2015
Highly Cited
2015
Miro1 deficiency in amyotrophic lateral sclerosis
Proper transportation of mitochondria to sites with high energy demands is critical for neuronal function and survival. Impaired… 
Highly Cited
2014
Highly Cited
2014
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Mutations in PINK1 and Parkin are associated with early-onset Parkinson's disease. We recently discovered that PINK1… 
Highly Cited
2013
Highly Cited
2013
DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking
Disrupted-In-Schizophrenia 1 (DISC1) is a candidate risk factor for schizophrenia, bipolar disorder and severe recurrent… 
2012
2012
RhoT1 and Smad4 Are Correlated with Lymph Node Metastasis and Overall Survival in Pancreatic Cancer
Cancer cell invasion and metastasis are the most important adverse prognostic factors for pancreatic cancer. Identification of… 
2011
2011
MIRO1 influences the morphology and intracellular distribution of mitochondria during embryonic cell division in Arabidopsis
Regulating the morphology and intracellular distribution of mitochondria is essential for embryo development in animals. However… 
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