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RHEB wt Allele

Known as: RHEB2, Ras Homolog Enriched In Brain 2 Gene, Ras Homolog Enriched In Brain wt Allele 
Human RHEB wild-type allele is located in the vicinity of 7q36 and is approximately 54 kb in length. This allele, which encodes GTP-binding protein… Expand
National Institutes of Health

Papers overview

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2014
2014
Background: Rheb activates mTORC1 to stimulate mRNA translation. Results: Rheb binds to CAD and activates CPSase activity… Expand
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2011
2011
Since cord blood (CB) has become a commonly used source of transplantable hematopoietic stem (HSC) and hematopoietic progenitor… Expand
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Highly Cited
2011
Highly Cited
2011
mTor kinase is involved in cell growth, proliferation, and differentiation. The roles of mTor activators, Rheb1 and Rheb2, have… Expand
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2011
2011
The insulin/Ras Homolog Enriched in Brain (Rheb)/Mammalian Target of Rapamycin (mTOR) pathway has been implicated in a variety of… Expand
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2009
2009
Molecular mechanisms preserving hematopoietic stem cell (HSC) self-renewal by maintaining a balance between proliferation… Expand
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2006
2006
Abstract : This report summarizes our accomplishments in characterizing the TSC/Rheb/mTOR signaling pathway that is altered in… Expand
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Highly Cited
2005
Highly Cited
2005
Lonafarnib (SCH66336) is a farnesyl transferase inhibitor (FTI) that inhibits the post-translational lipid modification of H-Ras… Expand
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Highly Cited
2003
Highly Cited
2003
Rheb GTPases represent a unique family of the Ras superfamily of G-proteins. Studies on Rheb in Schizosaccharomyces pombe and… Expand
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