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RFWD2 gene

Known as: RING FINGER AND WD REPEAT DOMAINS-CONTAINING PROTEIN 2, RNF200, COP1 
This gene is involved in the ubiquitination of target proteins.
National Institutes of Health

Related topics

Related topics

4 relations
RFWD2 protein, humanUbiquitinated Protein DegradationUbiquitinationconstitutive photomorphogenic 1 protein, Arabidopsis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
DHU1 negatively regulates UV-B signaling via its direct interaction with COP1 and RUP1.
2014
2014
In silico analysis of the structure and interaction of COP1 protein of Arabidopsis thaliana.
Previous studies have shown that COP1 (constitutive photomorphogenic 1) protein of Arabidopsis thaliana plays a crucial role in… 
2013
2013
The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy
BackgroundThe ubiquitin ligase COP1, COnstitutively Photomorphogenic 1, functions in many biological responses in mammalian cells… 
2013
2013
COP 1 targets C / EBP α for degradation and induces acute myeloid leukemia via Trib 1
The ubiquitin ligase COP1 is involved in many biological responses in mammalian cells, but its role in tumorigenesis remains… 
2013
2013
Loss of COP 1 expression determines poor prognosis in patients with gastric cancer
Previous studies have suggested conflicting roles for the E3 ubiquitin ligase COP1 in tumorigenesis, providing evidence that both… 
Review
2012
Review
2012
Developmental roles of tribbles protein family members
The gene tribbles (trbl), identified 12 years ago in genetic screens for mutations that control both cell division and cell… 
2011
2011
Mechanism of action of p28, a first-in-class, non-HDM2 mediated peptide inhibitor of p53 ubiquitination.
e13513 Background: Exposure of a wide variety of wild type and mutated p53 cancer cells to a 28 aa peptide (p28) derived from… 
Review
2005
Review
2005
Arabidopsis COP 1 protein specifically interacts in vitro with a cytoskeleton-associated protein , CIP 1 ( signal transduction / light regulation / coiled coil / plant development / subcellular…
Arabidopsis COP1 acts inside the nucleus to suppress photomorphogenic cellular development, and light inactivation of COP1 may… 
2000
2000
The Pea light-independent photomorphogenesis1 Mutant Results from Partial Duplication of COP1 Generating an Internal Promoter and Producing Two Distinct Transcripts
The pea lip1 (light-independent photomorphogenesis1) mutant shows many of the characteristics of light-grown development when… 
Highly Cited
1997
Highly Cited
1997
Genetic and Developmental Control of Nuclear Accumulation of COP1, a Repressor of Photomorphogenesis in Arabidopsis
Using a [beta]-glucuronidase (GUS) reporter-COP1 fusion transgene, it was shown previously that Arabidopsis COP1 acts within the… 
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