RFCNU

Known as: N-(2-chloroethyl)-1-ribofuranosyl-2',3'-isopropylidene-5'-(p-nitrobenzoate)-3-nitrosourea 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2006
012319752006

Papers overview

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1986
1986
2-Chloroethyl nitrosocarbamoylcystamine or ICIG-1325 (CNCC) is a lipid-soluble isomeric mixture of nitrosoureas. Its dose-effect… (More)
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1986
1986
Three new nitrosourea analogs (CNCC, RFCNU, and chlorozotocin) had comparable activities in vivo against L1210 leukemia cells. In… (More)
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1985
1985
L1210 leukemia was used to compare the antitumor activities of three nitrosoureas (chlorozotocin, RFCNU and CNCC) encapsulated in… (More)
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1983
1983
Three sugar derivatives of chloroethyl nitrosoureas: RPCNU, RFCNU and Chlorozotocin (CLZ) were examined for their effect on the… (More)
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1982
1982
The results of three phase II clinical trials with three new analogues belonging to the family of nitrosoureas are reported. One… (More)
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1980
1980
The disposition of 1-(2-chloroethyl)-3-[1'(5'-p-nitrobenzoyl-2',3'-isopropylidene)-alpha,beta-D-ribofuranosyl]-1-nitrosourea… (More)
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1979
1979
We have compared the LD50 of three new nitrosourea derivatives, RFCNU, RPCNU, and chlorozotocin (CZT), in L1210 leukemia-bearing… (More)
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1979
1979
Using high-performance liquid chromatography, the stability of RFCNU was monitored as a function of pH in aqueous buffers at 37… (More)
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1977
1977
RFCNU or (chloro-2-ethyl)-l-(ribofuranosyl-isopropylidene-2', 3' paranitrobenzoate-5')-3 nitrosourea, a new synthetic nitrosourea… (More)
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1975
1975
Four new nitrosourea derivatives represent an appreciable progress in the treatment and cure of L1210 leukemia. Their therapeutic… (More)
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