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RETNLB gene

Known as: RELMb, FOUND IN INFLAMMATORY ZONE 2, RESISTIN-LIKE MOLECULE-BETA 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
TGF-β1-induced SMAD2/3/4 activation promotes RELM-β transcription to modulate the endothelium-mesenchymal transition in human endothelial cells.
Endothelial-to-mesenchymal transition (EndMT), which is characterized by increased proliferation, migration and invasion of… Expand
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2016
2016
Acidic chitinase primes the protective immune response to gastrointestinal nematodes
Acidic mammalian chitinase (AMCase) is known to be induced by allergens and helminths, yet its role in immunity is unclear. Using… Expand
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2016
2016
Resistin-Like Molecule-β Promotes Invasion and Migration of Gastric Carcinoma Cells
BACKGROUND Resistin-like molecule-β (RELMβ) is a novel secretory protein from intestinal goblet cells and participates in… Expand
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2011
2011
FIZZ2/RELM-β induction and role in pulmonary fibrosis.
Found in inflammatory zone (FIZZ) 2, also known as resistin-like molecule (RELM)-β, belongs to a novel cysteine-rich secreted… Expand
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2007
2007
Resistin-like molecule beta (RELMbeta/FIZZ2) is highly expressed in the ileum of SAMP1/YitFc mice and is associated with initiation of ileitis.
SAMP1/Fc mice develop spontaneous ileitis that shares many features with human Crohn's disease. One of the earliest features of… Expand
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Highly Cited
2006
Highly Cited
2006
Absence of bacterially induced RELMbeta reduces injury in the dextran sodium sulfate model of colitis.
Although inflammatory bowel disease (IBD) is the result of a dysregulated immune response to commensal gut bacteria in… Expand
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Highly Cited
2005
Highly Cited
2005
Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells.
Ym1 and Fizz1 are secreted proteins that have been identified in a variety of Th2-mediated inflammatory settings. We originally… Expand
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Highly Cited
2004
Highly Cited
2004
RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract.
Gastrointestinal (GI) nematode infections are an important public health and economic concern. Experimental studies have shown… Expand
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Highly Cited
2003
Highly Cited
2003
The Th2 cell cytokines IL-4 and IL-13 regulate found in inflammatory zone 1/resistin-like molecule alpha gene expression by a STAT6 and CCAAT/enhancer-binding protein-dependent mechanism.
The onset of allergic inflammation in the lung is driven by a complex genetic program. This study shows that found in… Expand
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Highly Cited
2003
Highly Cited
2003
Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein.
BACKGROUND & AIMS Goblet cells are highly polarized exocrine cells found throughout the small and large intestine that have a… Expand
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