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REGN421

 
National Institutes of Health

Papers overview

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2016
2016
Delta-like ligand 4 (Dll4), one of the Notch ligands, is overexpressed in ovarian cancer, especially in tumors resistant to anti… Expand
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Highly Cited
2015
Highly Cited
2015
Purpose: Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody that binds human Dll4 and disrupts Notch-mediated… Expand
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2015
2015
The Notch ligand delta-like 4 (Dll4) has been identified as a promising target in tumor angiogenesis in preclinical studies, and… Expand
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2014
2014
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Purpose: To determine the effects of Dll4 blockade with… Expand
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2013
2013
Potent anti-tumor activity of blocking stromal Dll4 in ovarian xenograft models Delta-like ligand 4 (Dll4) is an emerging… Expand
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