REG proteasome activator subunit beta

The human immunodeficiency virus-1 Tat protein inhibits the peptidase activity of the 20S proteasome and competes with the 11S… Expand

The REG homologs, alpha, beta and gamma, activate mammalian proteasomes in distinct ways. REGalpha and REGbeta activate the… Expand

There are two immune responses in vertebrates: humoral immunity is mediated by circulating antibodies, whereas cytotoxic T… Expand

Proteasomes can be markedly activated by associating with 19S regulatory complexes to form the 26S protease or by binding 11S… Expand

The peptidase activities of eukaryotic proteasomes are markedly activated by the 11 S REG or PA28. The three identified REG… Expand

The specificity of the 20S proteasome, which degrades many intracellular proteins, is regulated by protein complexes that bind to… Expand

Full-length cDNAs for three human proteasome activator subunits, called REGalpha, REGbeta, and REGgamma, have been expressed in… Expand