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RB 6145

Known as: RB-6145 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

NitroimidazolesRadiation-Sensitizing Agents

Narrower (1)

PD 144872

Papers overview

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2006
2006
Nov-Dec 2006 Synthesis of the Enantiomers of the Dual Function 2-Nitroimidazole 1597 Radiation Sensitizer RB 6145
Short, efficient pathways are described for the synthesis of racemic 2-nitroimidazole radiation sensitizer RB-6145 (2a) and each… 
1995
1995
Chemosensitization of CCNU in KHT murine tumor cells in vivo and in vitro by the agent RB 6145 and its isomer PD 144872.
1994
1994
In vitro cytotoxicity and chemosensitizing activity of the dual function nitroimidazole RB 6145.
Review
1992
Review
1992
Failla Memorial Lecture. Redox, radiation, and reductive bioactivation.
A brief review is presented of the background to, and the principles involved in, the development of redox-sensitive drugs for… 
1992
1992
Dual function nitroimidazoles less toxic than RSU 1069: selection of candidate drugs for clinical trial (RB 6145 and/or PD 130908.
1990
1990
Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas.
The efficacies of a series of potential prodrugs of RSU-1069 and its alkyl-aziridine analogues were assessed. These 1-(2… 
1989
1989
Oncogenic transforming potential of nitroimidazole radiosensitizers.
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