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RAPGEF1 gene

Known as: GRF2, RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1, C3G 
This gene plays a role in signal transduction as well as protein binding and trafficking.
National Institutes of Health

Papers overview

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2017
2017
Background— Local ancestry may contribute to the disproportionate burden of subclinical and clinical cardiovascular disease among… Expand
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2011
2011
Type 2 diabetes is a common complex disorder with environmental and genetic components. The aim of the present study was to… Expand
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2011
2011
The guanine nucleotide exchange factor, C3G (RapGEF1), functions in multiple signaling pathways involved in cell adhesion… Expand
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2011
2011
RAPGEF1 (also known as C3G and GRF2) is a guanine nucleotide exchange factor that releases GDP from the inactive Rap1 protein… Expand
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2011
2011
Mutations in the CLN3 gene lead to juvenile neuronal ceroid lipofuscinosis, a pediatric neurodegenerative disorder characterized… Expand
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2011
2011
Cytoskeletal remodeling is responsible for cell plasticity and facilitates differentiation, motility and adherence related… Expand
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2011
2011
AIMS A study of 222 candidate genes in type 2 diabetes reported association of variants in RAPGEF1, ENPP1, TP53, NRF1, SLC2A2… Expand
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2009
2009
Under the activation of insulin receptors, glucose transporter 4 (Glut4) translocation is regulated by two signal transduction… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE Early/initiating oncogenic mutations have been identified for many cancers, but such mutations remain unidentified in… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Type 2 diabetes is a common complex disorder with environmental and genetic components. We used a candidate gene-based… Expand
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