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RAD51C gene

Known as: RAD51 Paralog C Gene, FANCO, RAD51, S. CEREVISIAE, HOMOLOG OF, C 
This gene plays a role in DNA repair and meiotic recombination.
National Institutes of Health

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Related topics

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DNA RepairFANCONI ANEMIA, COMPLEMENTATION GROUP OMeiotic RecombinationRAD51C protein, human

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RAD51C wt Allele

Papers overview

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2018
2018
Rice RAD51 paralogs play essential roles in somatic homologous recombination for DNA repair
Synthesis-dependent strand annealing (SDSA) and single-strand annealing (SSA) are the two main homologous recombination (HR… 
2018
2018
Gene‐panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication
Gene‐panel sequencing allows comprehensive analysis of multiple genes simultaneously and is now routinely used in clinical… 
2017
2017
BRCA1 and RAD51C promoter hypermethylation confer sensitivity to the PARP inhibitor rucaparib in patients with relapsed, platinum-sensitive ovarian carcinoma in ARIEL2 Part 1
2016
2016
Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer
Germ-line mutations in the RAD51C gene have recently been identified in families with breast and ovarian cancer and have been… 
2016
2016
High expression of Rad51c predicts poor prognostic outcome and induces cell resistance to cisplatin and radiation in non-small cell lung cancer
Rad51c is critical for homologous recombination repair and genomic stability and may play roles in tumorigenesis and cancer… 
2012
2012
Germline mutations in RAD51C in Jewish high cancer risk families
Germline mutations in BRCA1 and BRCA2 account for ~30 % of inherited breast cancer. RAD51C was reported as an additional breast… 
2006
2006
Lymphoblastoid cell lines differing in p53 status show clear differences in basal gene expression with minor changes after irradiation.
2005
2005
Cellular localization of human Rad51C and regulation of ubiquitin‐mediated proteolysis of Rad51
Rad51‐catalyzed homologous recombination is an important pathway for repair of DNA double strand breaks and maintenance of genome… 
2005
2005
Effect of Wortmannin on the repair profiles of DNA double-strand breaks in the whole genome and in interstitial telomeric sequences of Chinese hamster cells.
2004
2004
Spontaneous homologous recombination is decreased in Rad51C-deficient hamster cells.
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