RAD51C gene

Known as: RAD51 Paralog C Gene, FANCO, RAD51, S. CEREVISIAE, HOMOLOG OF, C 
This gene plays a role in DNA repair and meiotic recombination.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
0102019982018

Papers overview

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2012
2012
RAD51C was defined by Meindl et al. in 2010 as a high-risk gene involved in hereditary breast and ovarian cancers. Although this… (More)
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Highly Cited
2011
Highly Cited
2011
Inherited loss-of-function mutations in BRCA1 and BRCA2 and other tumor suppressor genes predispose to ovarian carcinomas, but… (More)
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Highly Cited
2011
Highly Cited
2011
A homozygous mutation in the RAD51C gene was recently found to cause Fanconi anemia-like disorder. Furthermore, six heterozygous… (More)
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Highly Cited
2010
Highly Cited
2010
Germline mutations in a number of genes involved in the recombinational repair of DNA double-strand breaks are associated with… (More)
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Highly Cited
2010
Highly Cited
2010
Fanconi anemia (FA) is a rare chromosomal-instability disorder associated with a variety of developmental abnormalities, bone… (More)
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Highly Cited
2004
Highly Cited
2004
During genetic recombination and the recombinational repair of chromosome breaks, DNA molecules become linked at points of strand… (More)
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2003
2003
In Drosophila, mutations in double-strand DNA break (DSB) repair enzymes, such as spn-B, activate a meiotic checkpoint leading to… (More)
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Highly Cited
2001
Highly Cited
2001
Cells defective in any of the RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) are sensitive to DNA cross-linking agents… (More)
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Highly Cited
2001
Highly Cited
2001
Five Rad51-like proteins, referred to as Rad51 paralogs, have been described in vertebrates. We show that two of them, Rad51B and… (More)
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2000
2000
Amplification of the 17q23 region occurs frequently in breast tumors. To characterize the structure of 17q23 amplicons and to… (More)
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