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RAC1 wt Allele

Known as: TC-25, CED10, C. elegans, Homolog of Gene, MIG5 
Human RAC1 wild-type allele is located in the vicinity of 7p22 and is approximately 29 kb in length. This allele, which encodes ras-related C3… 
National Institutes of Health

Related topics

Related topics

35 relations
7p22Agrin PathwayAngiotensin II Signaling PathwayApoptosis

Broader (2)

RAC1 generac1 GTP-Binding Protein

Papers overview

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Highly Cited
2014
Highly Cited
2014
Different design of enzyme-triggered CO-releasing molecules (ET-CORMs) reveals quantitative differences in biological activities in terms of toxicity and inflammation
Highly Cited
2013
Highly Cited
2013
Activation of Rac-1 and RhoA Contributes to Podocyte Injury in Chronic Kidney Disease
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and… 
2008
2008
Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes.
2007
2007
A novel mechanism of action for statins against diabetes-induced oxidative stress
Aims/hypothesisAtorvastatin exerts beneficial vascular effects in diabetes, but the underlying mechanisms are yet to be… 
Highly Cited
2006
Highly Cited
2006
Activation of Rac-1 and Cdc42 stabilizes the microvascular endothelial barrier
We have demonstrated previously that the Rho family GTPase Rac-1 is required for maintenance of endothelial barrier functions in… 
Highly Cited
2006
Highly Cited
2006
Selective Rac-1 Inhibition Protects From Diabetes-Induced Vascular Injury
Diabetes mellitus is a main risk factor for vascular diseases. Vascular injury induced by diabetes mellitus is characterized by… 
Highly Cited
2004
Highly Cited
2004
Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac‐1 GTPase, and NF‐kB transcription factor
Myogenesis is a multistep developmental program that generates and regenerates skeletal muscles. Several extracellular factors… 
2004
2004
Overexpression of Rac-1 small GTPase binding protein in oral squamous cell carcinoma.
Highly Cited
2003
Highly Cited
2003
Highly selective palladium catalyzed kinetic resolution and enantioselective substitution of racemic allylic carbonates with sulfur nucleophiles: asymmetric synthesis of allylic sulfides, allylic…
We describe the highly selective palladium catalyzed kinetic resolutions of the racemic cyclic allylic carbonates rac-1 a-c and… 
2000
2000
Mapping the binding site for the GTP-binding protein Rac-1 on its inhibitor RhoGDI-1.
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