R 1507

Known as: Anti-IGF-1R Monoclonal Antibody R1507, R-1507, R1507 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
024620092017

Papers overview

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2014
2014
BACKGROUND Insulin-like growth factor-1 receptor (IGF-1R) is implicated in the pathogenesis of rhabdomyosarcoma (RMS… (More)
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2013
2013
BACKGROUND Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and adolescents. Since survival… (More)
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2012
2012
Pancreatic cancer is a disease with a dismal prognosis and treatment options are limited. This study investigated the… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE R1507 is a selective, fully human, recombinant monoclonal antibody (immunoglobulin G1 subclass) against insulin-like… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE The type 1 insulin-like growth factor 1 receptor (IGF-1R) has been implicated in the pathogenesis of the Ewing sarcoma… (More)
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2011
2011
PURPOSE To investigate whether indium-111-labeled R1507 ((111)In-R1507) immuno-SPECT (single-photon emission computed tomography… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE A phase I study was conducted to evaluate the pharmacokinetics, pharmacodynamics, safety, and tolerability of R1507-a… (More)
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2010
2010
BACKGROUND The combination of rapamycin and R1507, a fully human IgG1 monoclonal antibody targeting the IGF-1 receptor (IGF-1R… (More)
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2010
2010
UNLABELLED The insulinlike growth factor 1 receptor (IGF-1R) is a new target for the treatment of breast cancer. Patients with… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The IGF receptor type 1 (IGF-1R) pathway is frequently deregulated in human tumors and has become a target of interest… (More)
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