Skip to search formSkip to main contentSkip to account menu

R 1507

Known as: Anti-IGF-1R Monoclonal Antibody R1507, R-1507, R1507 
National Institutes of Health

Related topics

Related topics

2 relations
RG 1507

Broader (1)

teprotumumab

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Abstract IA33: Combination targeted therapy in pediatric sarcomas
Our group, and many others have documented a crucial role for IGFIR signaling in several pediatric sarcomas. These studies, along… 
2013
2013
Large Molecule Therapeutics IGF-1 R Targeting Increases the Antitumor Effects of DNA-DamagingAgents in SCLCModel : AnOpportunity to Increase the Ef fi cacy of Standard Therapy
Insulin-like growth factor receptor-1 (IGF-1R) inhibition could be a relevant therapeutic approach in small cell lung cancer… 
2011
2011
PP 46 In vivo imaging of modulation of IGF-1R expression in breast cancer models
2011
2011
Abstract 1755: Sensitization of radiotherapy and chemotherapy by adjunction of R1507 (anti-IGF-1R monoclonal antibody) in small cell lung cancer cell lines: Opportunity of translating the triple…
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Introduction: Insulin like growth factor receptor-1… 
2011
2011
Abstract LB-397: Functional characterization of IGF-1R antibodies and possible implications for clinical safety and efficacy
Background This is the first study performing a head to head comparison of monoclonal IGF-1R antibodies (mAb) based on published… 
Highly Cited
2010
Highly Cited
2010
Fully Human Monoclonal Antibody Targeting IGF-1 R , Is Effective Alone and in Combination With Rapamycin in Inhibiting Growth of Osteosarcoma Xenografts
Osteosarcoma is the most common primary malignant bone tumor in children and young adults. The overall survival rate remains… 
2010
2010
ImmunoPET and immunoSPECT imaging of IGF-1R expression with radiolabeled R1507
2010
2010
Abstract A36: ImmunoSPECT and ImmunoPET imaging of IGF-1R expression in a model for triple negative breast cancer
Introduction: Triple negative breast cancer has a poor prognosis and chemotherapy is currently the mainstay of treatment. A… 
2009
2009
Expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507).
8095 Background: The IGF-1R (IGF receptor type 1) pathway is frequently deregulated in human tumors and has become a target of… 
2007
2007
A phase I study of q3W R1507, a human monoclonal antibody IGF-1R (insulin-like growth factor receptor) antagonist in patients with advanced solid tumors
A77 Background: Insulin-like growth factor receptor (IGF-1R) is a tyrosine kinase cell surface receptor frequently activated in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)