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R 125489

Known as: R-125489, R125489 
 
National Institutes of Health

Papers overview

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2011
2011
  • B. Mai, M. S. Li
  • Biochemical and biophysical research…
  • 2011
  • Corpus ID: 2627851
Two neuraminidase inhibitors, oseltamivir and zanamivir, are important drug treatments for influenza. Oseltamivir-resistant… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Antiviral drugs are an important option for managing infections caused by influenza viruses. This study assessed the… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for use… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT The neuraminidase inhibitors (NAIs) zanamivir and oseltamivir are currently the only antiviral drugs effective for the… Expand
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Highly Cited
2010
Highly Cited
2010
Currently, two neuraminidase (NA) inhibitors, oseltamivir and zanamivir, which must be administrated twice daily for 5 days for… Expand
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2010
2010
CS-8958, a prodrug of laninamivir (R-125489), is currently under development as an inhaled anti-influenza drug. In this study… Expand
Review
2010
Review
2010
  • M. Yamashita
  • Antiviral chemistry & chemotherapy
  • 2010
  • Corpus ID: 6155646
Oseltamivir and zanamivir are currently licensed worldwide for influenza treatment and chemoprophylaxis. Both drugs require twice… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT CS-8958 is a prodrug of the pharmacologically active form R-125489, a selective neuraminidase inhibitor, and has long… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for the… Expand
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2004
2004
Abstract R-118958 is a prodrug of R-125489, which is a neuraminidase inhibitor that potently inhibits influenza A and B viral… Expand