Quinolone Antibiotic

The basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
051019842018

Papers overview

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2014
2014
Plasma membrane pannexin 1 channels (PANX1) release nucleotide find-me signals from apoptotic cells to attract phagocytes. Here… (More)
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2014
2014
OBJECTIVES This study quantifies quinolone antibiotic resistance genes (qnrA and qnrS) in DNA of phage particles isolated from… (More)
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2011
2011
Quinolones inhibit bacterial type II DNA topoisomerases (e.g. DNA gyrase) and are among the most important antibiotics in current… (More)
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2008
2008
PURPOSE To determine differences in endophthalmitis rates with prophylactic use of third- versus fourth-generation… (More)
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Highly Cited
2006
Highly Cited
2006
The viral enzyme integrase is essential for the replication of human immunodeficiency virus type 1 (HIV-1) and represents a… (More)
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Highly Cited
2004
Highly Cited
2004
"Collateral damage" is a term used to refer to ecological adverse effects of antibiotic therapy; namely, the selection of drug… (More)
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2001
2001
Quinolones are clinically important antibiotic drugs. One quinolone antibiotic, sparfloxacin (SPX), has been recently reported to… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND On the basis of our concept that atherosclerosis has an immunopathological background, we tested whether activation of… (More)
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2001
2001
High rates of colonization and the challenge of managing Pseudomonas aeruginosa infections in patients with cystic fibrosis (CF… (More)
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1998
1998
Grepafloxacin (GPFX) has a comparatively greater hepatobiliary transport than other quinolone antibiotics. The biliary excretion… (More)
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