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Quinolone Antibiotic

The basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new… 
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
Administration of aerosolized antibiotics in cystic fibrosis patients.
High rates of colonization and the challenge of managing Pseudomonas aeruginosa infections in patients with cystic fibrosis (CF… 
2001
2001
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic.
The chronic toxicity and carcinogenicity of Moxifloxacin (MOX), a bacterial gyrase-inhibiting fluoroquinolone antibiotic, were… 
1997
1997
Characterization and interconversion of polymorphs of premafloxacin, a new quinolone antibiotic.
The quinolone antibiotic premafloxacin crystallizes in at least five solid modifications, including three anhydrous phases (Forms… 
1995
1995
Stereospecific high-performance liquid chromatographic assay of lomefloxacin in human plasma.
Highly Cited
1995
Highly Cited
1995
Pharmacokinetics and safety of trovafloxacin (CP-99, 219), a new quinolone antibiotic, following adminstration of single oral doses to healthy male volunteers
Trovafloxacin (CP-99,219) is a new fluoroquinolone antibacterial agent with a broad spectrum of activity against Gram-positive… 
1995
1995
Pharmacokinetics and safety of trovafloxacin (CP-99,219), a new quinolone antibiotic, following administration of single oral doses to healthy male volunteers.
Trovafloxacin (CP-99,219) is a new fluoroquinolone antibacterial agent with a broad spectrum of activity against Gram-positive… 
1995
1995
Enrofloxacin-theophylline interaction: influence of enrofloxacin on theophylline steady-state pharmacokinetics in the beagle dog.
Enrofloxacin, a quinolone antibiotic developed exclusively for use in animals, was investigated for its effects on the steady… 
1993
1993
Elimination of quinolone antibiotic carryover through use of antibiotic-removal beads
To prove the utility of antibiotic-removal beads in separating antibiotics from bacterial samples, Escherichia coli ATCC 25922… 
1991
1991
Successful treatment of methicillin-resistant Staphylococcus aureus Keratitis with topical ciprofloxacin.
1991
1991
Ciprofloxacin interaction with sodium warfarin: a potentially dangerous side effect.
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