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Quinacrine Mustard

Known as: 1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride, Mustard, Quinacrine, Quinacrine Mustard [Chemical/Ingredient] 
Nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. Fluoresces by reaction with nucleic… 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (1)

Acrichine Yperite

Broader (2)

Fluorescent DyesQuinacrine
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability.
Certain fluorescent DNA-binding compounds, among them quinacrine mustard and quinacrine, give characteristic banding patterns in… 
Review
2008
Review
2008
Chromosomal translocations: revisited yet again.
It is hard today, in 2008, when genetic changes in cancer and specifically hematologic malignancies are accepted as central… 
Highly Cited
2005
Highly Cited
2005
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins*
Tau protein is the major component of the intraneuronal filamentous inclusions that constitute defining neuropathological… 
Highly Cited
2004
Highly Cited
2004
Identification of human chromosomes by DNA-binding fluorescent agents
The distribution of DNA along metaphase chromosomes that are not excessively contracted can be visualized in the fluorescence… 
Highly Cited
1986
Highly Cited
1986
DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
Nitrogen mustards alkylate DNA primarily at the N7 position of guanine. Using an approach analogous to that of the Maxam-Gilbert… 
Highly Cited
1980
Highly Cited
1980
Specific cytogenetic changes in ovarian cancer involving chromosomes 6 and 14.
Cytogenetic studies were performed in 12 papillary serous adenocarcinomas of the ovary. Of the more than 19 clonal structural… 
Highly Cited
1972
Highly Cited
1972
Quinacrine mustard fluorescence of human chromosomes: characterization of unusual translocations.
  • U. Francke
  • American Journal of Human Genetics
  • 1972
  • Corpus ID: 44375001
Of the human metaphase chromosomes, only four autosomal pairs (nos. 1, 2, 3, and 16) and frequently the Y can be identified… 
Highly Cited
1970
Highly Cited
1970
Differential binding of alkylating fluorochromes in human chromosomes.
Highly Cited
1970
Highly Cited
1970
Technique for Identifying Y Chromosomes in Human Interphase Nuclei
CASPERSSON et al.1,2 have reported the staining of mitotic chromosomes in various organisms using fluorescent acridine… 
Highly Cited
1969
Highly Cited
1969
Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes.
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