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Quinacrine Mustard

Known as: 1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride, Mustard, Quinacrine, Quinacrine Mustard [Chemical/Ingredient] 
Nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. Fluoresces by reaction with nucleic… Expand
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (1)

Acrichine Yperite

Broader (2)

Fluorescent DyesQuinacrine
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Review
2008
Review
2008
Chromosomal translocations: revisited yet again.
It is hard today, in 2008, when genetic changes in cancer and specifically hematologic malignancies are accepted as central… Expand
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Highly Cited
2005
Highly Cited
2005
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins*
Tau protein is the major component of the intraneuronal filamentous inclusions that constitute defining neuropathological… Expand
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Highly Cited
2004
Highly Cited
2004
Identification of human chromosomes by DNA-binding fluorescent agents
The distribution of DNA along metaphase chromosomes that are not excessively contracted can be visualized in the fluorescence… Expand
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Highly Cited
2004
Highly Cited
2004
A system of nomenclature for band patterns of mouse chromosomes
Mouse chromosomes banded by quinacrine mustard staining, by the ASG technique, or by Giemsa staining following trypsinization or… Expand
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Highly Cited
1986
Highly Cited
1986
DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
Nitrogen mustards alkylate DNA primarily at the N7 position of guanine. Using an approach analogous to that of the Maxam-Gilbert… Expand
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1973
1973
The fluorescence of quinacrine mustard with nucleic acids.
CASPERSSON'S discovery1 of the differential fluorescence of chromosomes stained in situ with acridine dyes has made two… Expand
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Highly Cited
1972
Highly Cited
1972
The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability.
Certain fluorescent DNA-binding compounds, among them quinacrine mustard and quinacrine, give characteristic banding patterns in… Expand
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Highly Cited
1972
Highly Cited
1972
Quinacrine fluorescence of specific chromosome regions
The pattern of intense fluorescence of interphase nuclei and metaphase chromosomes after staining with quinacrine is described in… Expand
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Highly Cited
1970
Highly Cited
1970
Differential binding of alkylating fluorochromes in human chromosomes.
Abstract Human metaphase chromosomes from blood cultures, treated with quinacrine mustard (QM), show a banded pattern of… Expand
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Highly Cited
1970
Highly Cited
1970
Technique for Identifying Y Chromosomes in Human Interphase Nuclei
CASPERSSON et al.1,2 have reported the staining of mitotic chromosomes in various organisms using fluorescent acridine… Expand
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