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Quinacrine Mustard
Known as:
1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride
, Mustard, Quinacrine
, Quinacrine Mustard [Chemical/Ingredient]
Nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. Fluoresces by reaction with nucleic…
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National Institutes of Health
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Related topics
Related topics
7 relations
Narrower (1)
Acrichine Yperite
Broader (2)
Fluorescent Dyes
Quinacrine
analogs & derivatives
aspects of radiation effects
chemical synthesis
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
The 24 fluorescence patterns of the human metaphase chromosomes - distinguishing characters and variability.
T. Caspersson
,
G. Lomakka
,
L. Zech
Hereditas
2009
Corpus ID: 45168324
Certain fluorescent DNA-binding compounds, among them quinacrine mustard and quinacrine, give characteristic banding patterns in…
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Review
2008
Review
2008
Chromosomal translocations: revisited yet again.
J. Rowley
Blood
2008
Corpus ID: 9609297
It is hard today, in 2008, when genetic changes in cancer and specifically hematologic malignancies are accepted as central…
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Highly Cited
2005
Highly Cited
2005
Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins*
S. Taniguchi
,
N. Suzuki
,
+4 authors
M. Hasegawa
Journal of Biological Chemistry
2005
Corpus ID: 40225451
Tau protein is the major component of the intraneuronal filamentous inclusions that constitute defining neuropathological…
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Highly Cited
2004
Highly Cited
2004
Identification of human chromosomes by DNA-binding fluorescent agents
T. Caspersson
,
L. Zech
,
C. Johansson
,
E. Modest
Chromosoma
2004
Corpus ID: 25487074
The distribution of DNA along metaphase chromosomes that are not excessively contracted can be visualized in the fluorescence…
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Highly Cited
1986
Highly Cited
1986
DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
W. Mattes
,
J. Hartley
,
K. Kohn
Nucleic Acids Research
1986
Corpus ID: 9261518
Nitrogen mustards alkylate DNA primarily at the N7 position of guanine. Using an approach analogous to that of the Maxam-Gilbert…
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Highly Cited
1980
Highly Cited
1980
Specific cytogenetic changes in ovarian cancer involving chromosomes 6 and 14.
N. Wake
,
M. Hreshchyshyn
,
S. Piver
,
S. Matsui
,
A. Sandberg
Cancer Research
1980
Corpus ID: 10773758
Cytogenetic studies were performed in 12 papillary serous adenocarcinomas of the ovary. Of the more than 19 clonal structural…
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Highly Cited
1972
Highly Cited
1972
Quinacrine mustard fluorescence of human chromosomes: characterization of unusual translocations.
U. Francke
American Journal of Human Genetics
1972
Corpus ID: 44375001
Of the human metaphase chromosomes, only four autosomal pairs (nos. 1, 2, 3, and 16) and frequently the Y can be identified…
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Highly Cited
1970
Highly Cited
1970
Differential binding of alkylating fluorochromes in human chromosomes.
T. Caspersson
,
L. Zech
,
C. Johansson
Experimental Cell Research
1970
Corpus ID: 39839006
Highly Cited
1970
Highly Cited
1970
Technique for Identifying Y Chromosomes in Human Interphase Nuclei
P. Pearson
,
M. Bobrow
,
C. Vosa
Nature
1970
Corpus ID: 4013867
CASPERSSON et al.1,2 have reported the staining of mitotic chromosomes in various organisms using fluorescent acridine…
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Highly Cited
1969
Highly Cited
1969
Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes.
T. Caspersson
,
L. Zech
,
E. Modest
,
G. Foley
,
U. Wagh
,
E. Simonsson
Experimental Cell Research
1969
Corpus ID: 22432871
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