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Pyruvate Decarboxylase

Known as: Carboxy-Lyase, 2-Oxo Acid, Decarboxylase, Pyruvate, alpha Carboxylase 
Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Carboxy-Lyases
In BloodProcess of secretionPyruvateantagonists & inhibitors

Narrower (1)

PDC1 protein, S cerevisiae

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
The synthesis of yeast pyruvate decarboxylase is regulated by large variations in the messenger RNA level
SummaryThe yeast PDC1 gene coding for the fermentative enzyme pyruvate decarboxylase was isolated. This DNA sequence was used to… 
2003
2003
Histone H1 Is Required for Proper Regulation of Pyruvate Decarboxylase Gene Expression in Neurosporacrassa
ABSTRACT We show that Neurosporacrassa has a single histone H1 gene, hH1, which encodes a typical linker histone with highly… 
Highly Cited
2002
Highly Cited
2002
Spectroscopic evidence for participation of the 1',4'-imino tautomer of thiamin diphosphate in catalysis by yeast pyruvate decarboxylase.
The 1',4'-iminopyrimidine tautomeric form of the coenzyme thiamin diphosphate (ThDP), implicated in catalysis on the basis of the… 
Review
1997
Review
1997
Cofactor designing in functional analysis of thiamin diphosphate enzymes.
Highly Cited
1994
Highly Cited
1994
Substrate activation of brewers' yeast pyruvate decarboxylase is abolished by mutation of cysteine 221 to serine.
Brewers' yeast pyruvate decarboxylase (EC 4.1.1.1), a thiamin diphosphate and Mg(II)-dependent enzyme, isolated from… 
Highly Cited
1993
Highly Cited
1993
Alcohol dehydrogenase 2 and pyruvate decarboxylase induction in ripening and hypoxic tomato fruit
Alcohol dehydrogenase (alcohol: NAD + oxidoreductase; EC 1.1.1.1: ADH) isozyme 2 (ADH2), the isozyme induced in tomato… 
Highly Cited
1987
Highly Cited
1987
Alcohol Dehydrogenase and Pyruvate Decarboxylase Activity in Leaves and Roots of Eastern Cottonwood (Populus deltoides Bartr.) and Soybean (Glycine max L.).
Pyruvate decarboxylase (PDC, EC 4.1.1.1) and alcohol dehydrogenase (ADH, EC 1.1.1.1) are responsible for the anaerobic production… 
1983
1983
Carbon dioxide effects on ethanol production, pyruvate decarboxylase, and alcohol dehydrogenase activities in anaerobic sweet potato roots.
The effect of varied anaerobic atmospheres on the metabolism of sweet potato (Ipomoea batatas [L.] Lam.) roots was studied. The… 
Highly Cited
1983
Highly Cited
1983
An Expanded Concept for the Glucose Effect in the Yeast Saccharomyces uvarum: Involvement of Short- and Long-term Regulation
SUMMARY: When Saccharomyces uvarum was cultivated in continuous culture, it exhibited the typical growth behaviour of a glucose… 
1959
1959
Studies on the metabolism of Acetobacter peroxydans. II. The enzymic mechanism of lactate metabolism.
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