Pyrophosphate

In the wild tomato Solanum habrochaites, the Sst2 locus on chromosome 8 is responsible for the biosynthesis of several class II… (More)

The long-standing assumption that messenger RNA (mRNA) degradation in Escherichia coli begins with endonucleolytic cleavage has… (More)

Pyrophosphate is a potent inhibitor of medial vascular calcification where its level is controlled by hydrolysis via a tissue… (More)

Riboswitches are metabolite-sensing RNAs, typically located in the non-coding portions of messenger RNAs, that control the… (More)

Hyperphosphatemia is thought to underlie medial vascular calcification in advanced renal failure, but calcification can occur in… (More)

Tissue-nonspecific alkaline phosphatase (TNAP) hydrolyzes the mineralization inhibitor inorganic pyrophosphate (PP(i)). Deletion… (More)

The emerging antibiotics-resistance problem has underlined the urgent need for novel antimicrobial agents. Lantibiotics… (More)

Although proteins fulfil most of the requirements that biology has for structural and functional components such as enzymes and… (More)

Bisphosphonates (Bps), inhibitors of osteoclastic bone resorption, are used in the treatment of skeletal disorders. Recent… (More)

An approach for real-time DNA sequencing without the need for electrophoresis has been developed. The approach relies on the… (More)