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Purinergic P2 Receptor Antagonists

Known as: Antagonists, P2 Purinoceptor, Purinoceptor Antagonists, P2, Purinergic P2 Receptor Blockers 
Compounds that bind to and block the stimulation of PURINERGIC P2 RECEPTORS.
National Institutes of Health

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2,2'-pyridylisatogen tosylateINS 50589
In Bloodaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Highly Cited
2017
Highly Cited
2017
Endothelial Cell Autophagy Maintains Shear Stress–Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to Endothelial Nitric Oxide Synthase
Objective— Impaired endothelial cell (EC) autophagy compromises shear stress–induced nitric oxide (NO) generation. We determined… 
2005
2005
Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization.
Highly Cited
2003
Highly Cited
2003
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.
Review
1998
Review
1998
Evidence for three additional P2X2 purinoceptor isoforms produced by alternative splicing in the adult rat vestibular end-organs
Highly Cited
1997
Highly Cited
1997
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells
Highly Cited
1997
Highly Cited
1997
P2X7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore‐forming P2Z‐like phenotype
Highly Cited
1996
Highly Cited
1996
Identification of 6H1 as a P2Y purinoceptor: P2Y5.
We have determined the identity of the orphan G-protein coupled receptor cDNA, 6H1, present in activated chicken T cells, as a… 
1996
1996
Nucleotide-induced mucin release from primary hamster tracheal surface epithelial cells involves the P2u purinoceptor.
Mucin release by airway surface epithelial cells is regulated by extracellular adenosine triphosphate (ATP) via a P2 purinoceptor… 
1996
1996
A comparison of the binding characteristics of recombinant P2×1 and P2×2 purinoceptors
1 . We have recently provided evidence that [35S]‐adenosine 5′‐O‐[3‐thiotriphosphate] ([35S]‐ATPγS) can label the human bladder… 
1990
1990
Activation of early events of the mitogenic response by a P2Y purinoceptor with covalently bound 3'-O-(4-benzoyl)-benzoyladenosine 5'-triphosphate.
3'-O-(4-Benzoyl)benzoyl-ATP (BzATP), a photoaffinity analog of ATP, was used as a ligand for a P2Y purinoceptor (adenine… 
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