Purinergic P2 Receptor Antagonists
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Objective— Impaired endothelial cell (EC) autophagy compromises shear stress–induced nitric oxide (NO) generation. We determined… Expand The cytolytic P2X7 purinoceptor is widely expressed on leucocytes and has sparked interest because of its peculiar ability to… Expand T cells express a toxin-related ADP-ribosylating ectoenzyme, ART2. Exposure of mature T cells to NAD, the substrate for ADP… Expand P2X2 receptors are ligand-gated ion channels that are activated by extracellular ATP. To characterize the expression of P2X2… Expand
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The purinergic rP2X7 receptor expressed in a number of heterologous systems not only functions as a cation channel but also gives… Expand We have determined the identity of the orphan G-protein coupled receptor cDNA, 6H1, present in activated chicken T cells, as a… Expand Mucin release by airway surface epithelial cells is regulated by extracellular adenosine triphosphate (ATP) via a P2 purinoceptor… Expand 1 . We have recently provided evidence that [35S]‐adenosine 5′‐O‐[3‐thiotriphosphate] ([35S]‐ATPγS) can label the human bladder… Expand 3'-O-(4-Benzoyl)benzoyl-ATP (BzATP), a photoaffinity analog of ATP, was used as a ligand for a P2Y purinoceptor (adenine… Expand