FAQ

Purinergic P2 Receptor Antagonists

Known as: Antagonists, P2 Purinoceptor, Purinoceptor Antagonists, P2, Purinergic P2 Receptor Blockers 
Compounds that bind to and block the stimulation of PURINERGIC P2 RECEPTORS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
01219902017

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2,2'-pyridylisatogen tosylateINS 50589
In Bloodchemical synthesisisolation & purification analysisstandards characteristics

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Purinergic P2 Receptor Antagonists
In Blood
chemical synthesis
standards characteristics
2,2'-pyridylisatogen tosylate
INS 50589

Papers overview

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2017
2017
IL-27 enhances LPS-induced IL-1β in human monocytes and murine macrophages.
IL-27 bridges innate and adaptive immunity by modulating cytokine production from myeloid cells and regulating Th cell… (More)
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2015
2015
Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance.
Cell stress is implicated in triggering bouts of systemic inflammation in patients with autoinflammatory disorders. Blood… (More)
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2005
2005
Effect of adenosine triphosphate in renal ischemic injury: involvement of NF-kappaB.
Renal ischemic/reperfusion injury in vivo results in a significant increase of acute renal failure (ARF) and death. Nevertheless… (More)
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2000
2000
P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes.
ATP is known to act as an extracellular messenger mediating the propagation of Ca(2+) waves in astrocyte networks. ATP mediates… (More)
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1996
1996
Characterization of vascular P2 purinoceptors in the rat isolated perfused kidney.
In isolated, constant-pressure perfused rat kidneys at basal vascular tone, injected P2 purinoceptor agonists evoked… (More)
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1996
1996
Effect of extracellular ATP on cytosolic Ca2+ concentration in rat pulmonary artery myocytes.
Changes in cytosolic free Ca2+ concentration ([Ca2+]i) induced by ATP and other P2 purinoceptor agonists were investigated using… (More)
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1996
1996
P2x purinoceptor is not important in thymocyte apoptosis.
Since the P2X purinoceptor has been shown to be homologous with RP-2, a gene activated in thymocytes undergoing apoptosis after… (More)
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1995
1995
Pharmacological profile of the novel P2T-purinoceptor antagonist, FPL 67085 in vitro and in the anaesthetized rat in vivo.
1. The role of endogenous ADP in platelet aggregation in vivo remains unclear due to the lack of suitable P2T-antagonist probes… (More)
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1995
1995
Two different inhibitory effects of pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid on adenosine diphosphate-induced human platelet aggregation.
In the present study, the novel compound pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid (PPADS), which has been shown to… (More)
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1990
1990
Activation of early events of the mitogenic response by a P2Y purinoceptor with covalently bound 3'-O-(4-benzoyl)-benzoyladenosine 5'-triphosphate.
3'-O-(4-Benzoyl)benzoyl-ATP (BzATP), a photoaffinity analog of ATP, was used as a ligand for a P2Y purinoceptor (adenine… (More)
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