Purinergic P2 Receptor Antagonists

Objective— Impaired endothelial cell (EC) autophagy compromises shear stress–induced nitric oxide (NO) generation. We determined… Expand

Tissue factor (TF) is the high affinity receptor for factor VII (FVII)/VIIa [1]. It is expressed by cells surrounding blood… Expand

The laminar nerve endings are distributed in the laryngeal mucosa, and described as sensory receptors evoked by laryngeal… Expand

The cytolytic P2X7 purinoceptor is widely expressed on leucocytes and has sparked interest because of its peculiar ability to… Expand

T cells express a toxin-related ADP-ribosylating ectoenzyme, ART2. Exposure of mature T cells to NAD, the substrate for ADP… Expand

The human P2Y1 purinoceptor has been expressed in Jurkat cells and the effects of HPLC purified nucleotides on calcium movements… Expand

The purinergic rP2X7 receptor expressed in a number of heterologous systems not only functions as a cation channel but also gives… Expand

We have determined the identity of the orphan G-protein coupled receptor cDNA, 6H1, present in activated chicken T cells, as a… Expand

1. We have recently provided evidence that [35S]-adenosine 5'-O-[3-thiotriphosphate] ([35S]-ATP gamma S) can label the human… Expand

3'-O-(4-Benzoyl)benzoyl-ATP (BzATP), a photoaffinity analog of ATP, was used as a ligand for a P2Y purinoceptor (adenine… Expand