Puma <Felidae>

Known as: Herpailurus, Puma, Pumas 
A genus in the family FELIDAE comprising one species, Puma concolor. It is a large, long-tailed, feline of uniform color. The names puma, cougar, and… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
The rediscovery of remnant Florida panthers (Puma concolor coryi) in southern Florida swamplands prompted a program to protect… (More)
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Highly Cited
2006
Highly Cited
2006
The ability of p53 to induce apoptosis plays an important role in tumor suppression. Here, we describe a previously unknown… (More)
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Highly Cited
2006
Highly Cited
2006
Puma is an essential mediator of p53-dependent and -independent apoptosis in vivo. In response to genotoxic stress, Puma is… (More)
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Review
2006
Review
2006
Individual BCL2 family members couple apoptosis regulation and cell cycle control in unique ways. Antiapoptotic BCL2 and BCL-xL… (More)
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Highly Cited
2005
Highly Cited
2005
In response to DNA damage, the p53 tumor suppressor can elicit either apoptosis or cell-cycle arrest and repair, but how this… (More)
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Highly Cited
2005
Highly Cited
2005
As a treatment for dyslipidemia, oral doses of 1-3 grams of nicotinic acid per day lower serum triglycerides, raise high density… (More)
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Highly Cited
2004
Highly Cited
2004
p73, an important developmental gene, shares a high sequence homology with p53 and induces both G(1) cell cycle arrest and… (More)
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Highly Cited
2003
Highly Cited
2003
Apoptosis provoked by DNA damage requires the p53 tumor suppressor, but which of the many p53-regulated genes are required has… (More)
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Highly Cited
2003
Highly Cited
2003
Nicotinic acid (niacin), a vitamin of the B complex, has been used for almost 50 years as a lipid-lowering drug. The… (More)
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Highly Cited
2003
Highly Cited
2003
Although several genes that might mediate p53-induced apoptosis have been proposed, none have previously been shown to play an… (More)
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