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The major sites of obstruction in chronic obstructive pulmonary disease (COPD) are small airways (<2 mm in diameter… Expand Chronic obstructive pulmonary disease and emphysema are common destructive inflammatory diseases that are leading causes of death… Expand The syndrome resulting from combined pulmonary fibrosis and emphysema has not been comprehensively described. The current authors… Expand Although inflammation and protease/antiprotease imbalance have been postulated to be critical in cigarette smoke-induced (CS… Expand BACKGROUND
Lung-volume-reduction surgery has been proposed as a palliative treatment for severe emphysema. Effects on mortality… Expand Pulmonary emphysema, a significant global health problem, is characterized by a loss of alveolar structures. Because VEGF is a… Expand Chronic obstructive pulmonary disease (COPD) is a common problem in the elderly. The disease is characterised by intermittent… Expand A new gene, termed klotho, has been identified that is involved in the suppression of several ageing phenotypes. A defect in… Expand To determine which proteinases are responsible for the lung destruction characteristic of pulmonary emphysema, macrophage… Expand High-resolution computed tomography (HRCT) scans were obtained at 1 cm intervals in 63 subjects referred for surgical resection… Expand