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Proto-Oncogene Proteins c-rel

Known as: rel Proto Oncogene Product p68, p68 c-rel, c-rel Proteins 
Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in… 
National Institutes of Health

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I-kappa B ProteinsIn BloodProcess of secretionagonists

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Highly Cited
2003
Highly Cited
2003
Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel−/− B cells
Aberrant overexpression of the c-rel protooncogene is associated with lymphoid malignancy, while c-rel deletion produces severe… 
Highly Cited
1996
Highly Cited
1996
Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product
The product of the c-rel proto-oncogene (c-Rel) belongs to the NF-kappaB/Rel family of polypeptides and has been implicated in… 
Highly Cited
1993
Highly Cited
1993
v-Rel and c-Rel are differentially affected by mutations at a consensus protein kinase recognition sequence.
The avian retroviral oncoprotein v-Rel and its cellular homolog c-Rel are members of a family of related site-specific DNA… 
Highly Cited
1993
Highly Cited
1993
rel/NF-kappa B nuclear complexes that bind kB sites in the murine c-rel promoter are required for constitutive c-rel transcription in B-cells.
The c-rel protooncogene, a member of a transcription factor family that includes NF-kappa B, displays a complex pattern of gene… 
Highly Cited
1990
Highly Cited
1990
Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts.
We isolated and sequenced a 3727 bp clone of the c-rel proto-oncogene from a chicken embryo fibroblast (CEF) cDNA library… 
1990
1990
Identification of protein complexes containing the c-rel proto-oncogene product in avian hematopoietic cells.
The c-rel proto-oncogene product has been identified as a 75 kDa protein expressed in lymphoid cells transformed by REV-T and… 
Highly Cited
1990
Highly Cited
1990
Avian reticuloendotheliosis virus-transformed lymphoid cells contain multiple pp59v-rel complexes
The v-rel oncogene of avian reticuloendotheliosis virus type T (REV-T) encodes a 59-kilodalton (kDa) phosphoprotein located… 
Highly Cited
1989
Highly Cited
1989
Structure of a mammalian c-rel protein deduced from the nucleotide sequence of murine cDNA clones.
The avian retrovirus, rev-T, which carries the viral oncogene v-rel, causes an acute leukemia in birds and transforms immature… 
Highly Cited
1988
Highly Cited
1988
p59v-rel, the transforming protein of reticuloendotheliosis virus, is complexed with at least four other proteins in transformed chicken lymphoid cells
Previous studies have identified the protein product of v-rel, the oncogene carried by reticuloendotheliosis virus (REV), as a 59… 
Highly Cited
1987
Highly Cited
1987
Enzyme-linked synthetic oligonucleotide probes: non-radioactive detection of enterotoxigenic Escherichia coli in faecal specimens
Synthetic oligonucleotides, complementary to unique sequences in the heat stable enterotoxin gene of Escherichia coli specific… 
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