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Proto-Oncogene Proteins c-myb
Known as:
myb, Proto-Oncogene Proteins
, myb Proto-Oncogene Proteins
, Proto-Oncogene Proteins myb
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Cellular DNA-binding proteins encoded by the myb gene (GENES, MYB). They are expressed in a wide variety of cells including thymocytes and…
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National Institutes of Health
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Related topics
Related topics
26 relations
Acute lymphocytic leukemia
Cell Differentiation process
Cell Nucleus
Cell Proliferation
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CPC protein, Arabidopsis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia
I. Lahortiga
,
K. De Keersmaecker
,
+15 authors
J. Cools
Nature Genetics
2007
Corpus ID: 7718893
We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in…
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Highly Cited
2003
Highly Cited
2003
Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c‐Myb
Nikla R. Emambokus
,
A. Vegiopoulos
,
Benjamin C Harman
,
E. Jenkinson
,
G. Anderson
,
J. Frampton
EMBO Journal
2003
Corpus ID: 32119737
The c‐Myb transcription factor is expressed in immature haemopoietic cells and at key stages during differentiation. Loss of the…
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Highly Cited
2003
Highly Cited
2003
Integration of Wounding and Osmotic Stress Signals Determines the Expression of the AtMYB102 Transcription Factor Gene1
M. Denekamp
,
S. Smeekens
Plant Physiology
2003
Corpus ID: 23657264
Transcript levels of the Arabidopsis R2R3-AtMYB102 transcription factor gene, previously named AtM4, are rapidly induced by…
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Highly Cited
2002
Highly Cited
2002
Proteomics Analysis Reveals Stable Multiprotein Complexes in Both Fission and Budding Yeasts Containing Myb-Related Cdc5p/Cef1p, Novel Pre-mRNA Splicing Factors, and snRNAs
M. Ohi
,
Andrew J. Link
,
L. Ren
,
Jennifer L. Jennings
,
W. H. McDonald
,
Kathleen L. Gould
Molecular and Cellular Biology
2002
Corpus ID: 16010851
ABSTRACT Schizosaccharomyces pombe Cdc5p and its Saccharomyces cerevisiae ortholog, Cef1p, are essential Myb-related proteins…
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Highly Cited
2002
Highly Cited
2002
Covalent Attachment of the SUMO-1 Protein to the Negative Regulatory Domain of the c-Myb Transcription Factor Modifies Its Stability and Transactivation Capacity*
J. Bies
,
J. Markus
,
L. Wolff
Journal of Biological Chemistry
2002
Corpus ID: 25150417
The transcription factor c-Myb is subject to several types of post-translational modifications, including phosphorylation…
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Highly Cited
2002
Highly Cited
2002
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis
L. Kasper
,
F. Boussouar
,
+4 authors
Paul K. Brindle
Nature
2002
Corpus ID: 4388401
The coactivators CBP (Cre-element binding protein (CREB)-binding protein) and its paralogue p300 are thought to supply adaptor…
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Highly Cited
1996
Highly Cited
1996
A dominant interfering Myb mutant causes apoptosis in T cells.
Deborah Taylor
,
P. Badiani
,
Kathleen Weston
Genes & Development
1996
Corpus ID: 7976697
The c-Myb transcription factor is required for the production of most hemopoietic lineages, but information is sparse about its…
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Highly Cited
1996
Highly Cited
1996
v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells.
Jon Frampton
,
rn Ramqvist
,
Thomas Graf
Genes & Development
1996
Corpus ID: 11673206
Many oncogenes have been shown to be deregulated transcription factors, yet direct target genes mediating cell transformation…
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Highly Cited
1990
Highly Cited
1990
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
B. Lüscher
,
E. Christenson
,
D. Litchfield
,
E. Krebs
,
R. Eisenman
Nature
1990
Corpus ID: 4232788
The c-Myb nuclear oncoprotein is phosphorylated in vitro and in vivo at an N-terminal site near its DNA-binding domain by casein…
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Highly Cited
1989
Highly Cited
1989
An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.
G. Anfossi
,
A. Gewirtz
,
B. Calabretta
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 39117142
To study the role of the protooncogene c-myb in regulating myeloid leukemia cell proliferation and differentiation, we exposed…
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