Proto-Oncogene Proteins c-bcr

Known as: c-bcr, Proto-Oncogene Protein, Proto-Oncogene Proteins, c-bcr, c-bcr Proteins 
A serine-threonine kinase that contains a C2 DOMAIN and PLECKSTRIN HOMOLOGY DOMAIN. It also has activity as a GTPASE-ACTIVATING PROTEIN for RAC1… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
In the face of competing first-line treatment options for CML, early prediction of prognosis on imatinib is desirable to assure… (More)
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Highly Cited
2012
Highly Cited
2012
The molecular crosstalk between the interleukin 7 receptor (IL-7R) and the precursor to the B cell antigen receptor (pre-BCR) in… (More)
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Highly Cited
2007
Highly Cited
2007
Ikaros DNA-binding proteins are critical for the development of lymphocytes and other hematopoietic lineages, but it remains… (More)
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Review
2004
Review
2004
Chronic myelogenous leukemia (CML) evolves from a chronic phase characterized by the Philadelphia chromosome as the sole genetic… (More)
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Highly Cited
2002
Highly Cited
2002
The developmental progression from pro-B to pre-B cells is controlled by pre-B cell receptor (pre-BCR) signaling which depends on… (More)
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Highly Cited
2002
Highly Cited
2002
Multipotent neural stem cells (NSCs) present in the developing neural tube (E10.5, neuroepithelial cells; NEP) were examined for… (More)
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Highly Cited
2000
Highly Cited
2000
Pre-B cell receptor (pre-BCR) expression is critical for B lineage development. The signaling events initiated by the pre-BCR… (More)
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Highly Cited
2000
Highly Cited
2000
The capacity of precursor B (pre-B) I cells from fetal liver and bone marrow to proliferate and differentiate into surface… (More)
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Highly Cited
1993
Highly Cited
1993
Although the BCR-ABL hybrid gene on chromosome 22q-plays a pivotal role in the pathogenesis of chronic myeloid leukemia (CML… (More)
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Highly Cited
1991
Highly Cited
1991
Sequences encoded by the first exon of BCR that bind to the ABL SH2 domain are essential for the activation of the ABL tyrosine… (More)
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