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Protein-arginine deiminase

Known as: peptidylarginine deiminase, protein-L-arginine iminohydrolase 
 
National Institutes of Health

Related topics

Related topics

4 relations
Arginine deiminasePADI4 gene

Broader (1)

Hydrolase

Narrower (1)

PADI2 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice
Deep vein thrombosis and pulmonary embolism are major health problems associated with high mortality. Recently, DNA-based… Expand
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Highly Cited
2009
Highly Cited
2009
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
Peripheral blood neutrophils form highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs), that… Expand
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Highly Cited
2008
Highly Cited
2008
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
Objectives: A gene–environment interaction between HLA-DR shared epitope genes and smoking in anti-cyclic citrullinated peptide… Expand
Highly Cited
2007
Highly Cited
2007
Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro.
Peptidylarginine deiminase (PAD) enzymes catalyze the conversion of arginine residues in proteins to citrulline residues… Expand
Highly Cited
2004
Highly Cited
2004
Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination
Methylation of arginine (Arg) and lysine residues in histones has been correlated with epigenetic forms of gene regulation… Expand
Highly Cited
2004
Highly Cited
2004
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages.
BACKGROUND Antibodies directed to proteins containing the non-standard amino acid citrulline, are extremely specific for… Expand
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Review
2004
Review
2004
Hypothesis: The Humoral Immune Response to Oral Bacteria Provides a Stimulus for the Development of Rheumatoid Arthritis
Rheumatoid arthritis (RA) and adult periodontitis share common pathogenetic mechanisms and immunologic and pathological findings… Expand
Highly Cited
2002
Highly Cited
2002
Nuclear Localization of Peptidylarginine Deiminase V and Histone Deimination in Granulocytes*
Peptidylarginine deiminase (PAD) deiminates arginine residues in proteins to citrulline residues Ca2+ dependently. There are four… Expand
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Highly Cited
1999
Highly Cited
1999
Purification, Characterization, and Sequence Analysis of a Potential Virulence Factor from Porphyromonas gingivalis, Peptidylarginine Deiminase
ABSTRACT The initiation and progression of adult-onset periodontitis has been associated with infection of the gingival sulcus… Expand
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Highly Cited
1996
Highly Cited
1996
Protein Unfolding by Peptidylarginine Deiminase
Peptidylarginine deiminases, which are commonly found in mammalian cells, catalyze the deimination of protein-bound arginine… Expand
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