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Protein-arginine deiminase

Known as: peptidylarginine deiminase, protein-L-arginine iminohydrolase 
National Institutes of Health

Related topics

Related topics

4 relations
Arginine deiminasePADI4 gene

Broader (1)

Hydrolase

Narrower (1)

PADI2 protein, human

Papers overview

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Highly Cited
2014
Highly Cited
2014
Citrullinated Glucose-Regulated Protein 78 Is an Autoantigen in Type 1 Diabetes
Posttranslational modifications of self-proteins play a substantial role in the initiation or propagation of the autoimmune… 
Highly Cited
2012
Highly Cited
2012
Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity*
Background: Histone citrullination by PAD4 regulates tumor suppressor gene expression. Results: The novel PAD inhibitor YW3-56… 
Highly Cited
2011
Highly Cited
2011
PAD4-Mediated Neutrophil Extracellular Trap Formation Is Not Required for Immunity against Influenza Infection
During an inflammatory response, neutrophils migrate to the site of infection where they can kill invading pathogens by… 
Review
2010
Review
2010
Peptidylarginine deiminase 4 and citrullination in health and disease.
Highly Cited
2008
Highly Cited
2008
Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4
ABSTRACT Histone Arg methylation has been correlated with transcriptional activation of p53 target genes. However, whether this… 
Highly Cited
2007
Highly Cited
2007
Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro.
Highly Cited
2006
Highly Cited
2006
Increased Citrullination of Histone H3 in Multiple Sclerosis Brain and Animal Models of Demyelination: A Role for Tumor Necrosis Factor-Induced Peptidylarginine Deiminase 4 Translocation
Modification of arginine residues by citrullination is catalyzed by peptidylarginine deiminases (PADs), of which five are known… 
Highly Cited
2004
Highly Cited
2004
Dynamic alterations of specific histone modifications during early murine development
In order to investigate whether covalent histone modifications may be involved in early embryonic reprogramming events, changes… 
Highly Cited
2000
Highly Cited
2000
Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D.
The effect of deimination of arginyl residues in bovine myelin basic protein (MBP) on its susceptibility to digestion by… 
Highly Cited
1991
Highly Cited
1991
Three types of mouse peptidylarginine deiminase: characterization and tissue distribution.
Three types of mouse peptidylarginine deiminase were separated by DEAE-Sephacel ion-exchange column chromatography, and we… 
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