Protein Sprouty Homolog 2

Known as: SPRY2, Sprouty 2, Spry-2 
Protein sprouty homolog 2 (315 aa, ~35 kDa) is encoded by the human SPRY2 gene. This protein is involved in antagonism of growth factor signaling… (More)

Topic mentions per year

Topic mentions per year

2000-2017
05101520002017

Papers overview

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2013
2013
Emerging evidence indicates that the miR-23a/24-2/27a cluster may possess a causal role in mammary tumorigenesis and function as… (More)
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2011
2011
BACKGROUND & AIMS The concept of multistep hepatocarcinogenesis has been well-established, and an accumulation of methylating… (More)
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2011
2011
Sprouty 2 is a key antagonist regulator of receptor tyrosine kinases, and downstream signaling pathways, like fibroblastic growth… (More)
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Highly Cited
2010
Highly Cited
2010
Hypoxia stimulates pulmonary artery smooth muscle cell (PASMC) proliferation. Recent studies have implicated an important role… (More)
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2008
Highly Cited
2008
The posttranscriptional regulator, microRNA-21 (miR-21), is up-regulated in many forms of cancer, as well as during cardiac… (More)
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Highly Cited
2006
Highly Cited
2006
The Sprouty proteins are increasingly being recognized to be deregulated in various types of cancers. This deregulation is often… (More)
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2006
2006
Sprouty family proteins are novel regulators of growth factor actions. Human Sprouty 2 (hSPRY2) inhibits the proliferation of a… (More)
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2006
2006
Sprouty proteins encoded by the SPRY genes act as modulators and feedback inhibitors of signalling by epidermal growth factor… (More)
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2004
2004
BRAF mutations result in constitutively active BRAF kinase activity and increased extracellular signal-regulated kinase (ERK… (More)
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2004
2004
The kidney is a classic model for studying mechanisms of inductive tissue interactions associated with the epithelial branching… (More)
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