Protein Overexpression

Known as: Overexpression, overexpress 
In biology, to make too many copies of a protein or other substance. Overexpression of certain proteins or other substances may play a role in cancer… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Virtually, all tumor cells as well as all immune cells express plasma membrane receptors for extracellular nucleosides (adenosine… (More)
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Highly Cited
2008
Highly Cited
2008
A simple generic method for optimizing membrane protein overexpression in Escherichia coli is still lacking. We have studied the… (More)
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Review
2006
Review
2006
Functional and structural studies of membrane proteins usually require overexpression of the proteins in question. Often, however… (More)
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Highly Cited
2005
Highly Cited
2005
To determine the role of reactive oxygen species in mammalian longevity, we generated transgenic mice that overexpress human… (More)
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Highly Cited
2001
Highly Cited
2001
The cyclooxygenase (COX)-2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and… (More)
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Highly Cited
2001
Highly Cited
2001
At least two temporally and mechanistically distinct forms of memory are conserved across many species: short-term memory that… (More)
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Highly Cited
1991
Highly Cited
1991
The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could… (More)
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Highly Cited
1991
Highly Cited
1991
The BCL2 protooncogene encodes an inner mitochondrial membrane protein that blocks programmed cell death. BCL2 was isolated from… (More)
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Highly Cited
1990
Highly Cited
1990
In order to investigate the prognostic significance of erbB-2 overexpression, immunohistochemical staining for the erbB-2 protein… (More)
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Highly Cited
1988
Highly Cited
1988
Amplification of the neu proto-oncogene in breast cancer has been reported to correlate with the presence of lymph-node… (More)
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