Protein Misfolding Disorders

Known as: Protein Folding Disease, Misfolding Diseases, Protein, Protein Misfolding Disease 
Disorders caused by dysfunctions in PROTEIN FOLDING and degradation or clearance of misfolded proteins.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Eukaryotic cells are partitioned into functionally distinct self-organizing compartments. But while the biogenesis of membrane… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2009
Review
2009
Protein Misfolding Disorders (PMDs) are a group of diseases characterized by the accumulation of abnormally folded proteins… (More)
Is this relevant?
Review
2009
Review
2009
The autoinflammatory diseases are characterized by seemingly unprovoked episodes of inflammation, without high-titer… (More)
Is this relevant?
Review
2009
Review
2009
Protein misfolding and aggregation are pathognomic for a number of the most common age-related degenerative diseases. Great… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The accumulation of β-sheet–rich amyloid fibrils or aggregates is a complex, multistep process that is associated with cellular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2006
Review
2006
Protein misfolding is a common event in living cells. In young and healthy cells, the misfolded protein load is disposed of by… (More)
Is this relevant?
Review
2006
Review
2006
Newly synthesized proteins in the living cell must go through a folding process to attain their functional structure. To achieve… (More)
  • figure 1
  • figure 2
Is this relevant?
Review
2005
Review
2005
Small molecule-mediated protein stabilization inside or outside of the cell is a promising strategy to treat protein misfolding… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Amyloid fibrillization is multistep process involving soluble oligomeric intermediates, including spherical oligomers and… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
A range of human degenerative conditions, including Alzheimer's disease, light-chain amyloidosis and the spongiform… (More)
  • figure 1
  • figure 3
  • figure 2
Is this relevant?