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Protein Misfolding Disorders

Known as: Protein Folding Disease, Misfolding Diseases, Protein, Protein Misfolding Disease 
Disorders caused by dysfunctions in PROTEIN FOLDING and degradation or clearance of misfolded proteins.
National Institutes of Health

Papers overview

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2015
2015
Pathogenic aggregation is closely associated with various protein misfolding diseases such as type 2 diabetes mellitusand… 
Highly Cited
2012
Highly Cited
2012
Recent evidence suggests that simple peptides can access diverse amphiphilic phases, and that these structures underlie the… 
2011
2011
Reece et al report that single-agent bortezomib resulted in hematologic responses in two-thirds of patients with relapsed Light… 
Highly Cited
2010
Highly Cited
2010
Access to native protein structure depends on precise polypeptide folding and assembly pathways. Identifying folding missteps… 
Highly Cited
2009
Highly Cited
2009
An R120G mutation in &agr;B-crystallin (CryABR120G) causes desmin-related myopathy (DRM). In mice with cardiomyocyte-specific… 
Highly Cited
2009
Highly Cited
2009
Transthyretin (TTR) is one of thirty non-homologous proteins whose misfolding, dissociation, aggregation, and deposition is… 
2009
2009
Protein misfolding and aggregation can lead to several neurodegenerative diseases including Alzheimer's Disease (AD), Parkinson's… 
Highly Cited
2003
Highly Cited
2003
Calreticulin is an endoplasmic reticulum (ER) luminal Ca2+-binding chaperone involved in folding of newly synthesized…