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Protein Misfolding Disorders

Known as: Protein Folding Disease, Misfolding Diseases, Protein, Protein Misfolding Disease 
Disorders caused by dysfunctions in PROTEIN FOLDING and degradation or clearance of misfolded proteins.
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Proteostasis Deficiencies

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Type 2 diabetes as a protein misfolding disease.
Highly Cited
2013
Highly Cited
2013
Salt stress triggers phosphorylation of the Arabidopsis vacuolar K+ channel TPK1 by calcium-dependent protein kinases (CDPKs).
14-3-3 proteins play an important role in the regulation of many cellular processes. The Arabidopsis vacuolar two-pore K… 
Highly Cited
2011
Highly Cited
2011
A Parallel Microfluidic Flow Cytometer for High Content Screening
A parallel microfluidic cytometer (PMC) uses a high-speed scanning photomultiplier-based detector to combine low-pixel-count, one… 
Review
2010
Review
2010
Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth
Review
2009
Review
2009
Development of tau aggregation inhibitors for Alzheimer's disease.
A variety of human diseases are suspected to be directly linked to protein misfolding. Highly organized protein aggregates… 
Review
2008
Review
2008
Molecular and cellular aspects of protein misfolding and disease
Proteins are essential elements for life. They are building blocks of all organisms and the operators of cellular functions… 
Review
2008
Review
2008
Recent Insights in Islet Amyloid Polypeptide-Induced Membrane Disruption and Its Role in β-Cell Death in Type 2 Diabetes Mellitus
The presence of fibrillar protein deposits (amyloid) of human islet amyloid polypeptide (hIAPP) in the pancreatic islets of… 
Review
2005
Review
2005
Directed evolution of enzyme stability.
Highly Cited
2000
Highly Cited
2000
Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism.
Amyloid plaques composed of the peptide Abeta are an integral part of Alzheimer's disease (AD) pathogenesis. We have modeled the… 
Review
2000
Review
2000
Protein folding: progress made and promises ahead.
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