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Protein Lin-28 Homolog B

Known as: Lin-28B 
Protein lin-28 homolog B (250 aa, ~27 kDa) is encoded by the human LIN28B gene. This protein plays a role in the degradation of pre-miRNA.
National Institutes of Health

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Related topics

7 relations
Cell NucleusCytoplasmGenes, RegulatorLIN28A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Mutual suppression of miR-125a and Lin28b in human hepatocellular carcinoma cells.
2016
2016
Abstract 4831: An investigation to study the role of novel rhenium compounds on onco miR's and oncogenes involved in epithelial mesenchymal transition of prostate cancer cell lines derived from…
In this research, we seek to evaluate the efficacy of novel rhenium compounds as a novel targeted agent against prostate cancer… 
Highly Cited
2013
Highly Cited
2013
Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition
Inflammation can act as a crucial mediator of epithelial-to-mesenchymal transition (EMT). In this study, we show that oncostatin… 
2012
2012
Regulation of the let-7a-3 Promoter by NF-κB
Changes in microRNA expression have been linked to a wide array of pathological states. However, little is known about the… 
Review
2012
Review
2012
LIN28B (lin-28 homolog B (C. elegans))
Review on LIN28B (lin-28 homolog B (C. elegans)), with data on DNA, on the protein encoded, and where the gene is implicated. 
2012
2012
Abstract 3655: Stem cell-associated gene Lin-28B genotype and phenotype in epithelial ovarian cancer and their associations with disease survival outcomes
Several single nucleotide polymorphisms (SNPs) in lin-28B, a gene encoding RNA binding protein that represses miRNA let-7… 
Highly Cited
2011
Highly Cited
2011
IMP-1 displays cross-talk with K-Ras and modulates colon cancer cell survival through the novel proapoptotic protein CYFIP2.
Insulin-like growth factor 2 mRNA-binding protein-1 (IMP-1) is an oncofetal protein that binds directly to and stabilizes… 
2011
2011
Molecular and Cellular Pathobiology IMP-1 Displays Cross-Talk with KRas and Modulates Colon Cancer Cell Survival through the Novel Proapoptotic Protein CYFIP 2
Insulin-like growth factor 2 mRNA-binding protein-1 (IMP-1) is an oncofetal protein that binds directly to and stabilizes… 
Highly Cited
2009
Highly Cited
2009
Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.
2009
2009
Tumors line up for a letdown
MicroRNAs (miRNAs) and the pathways that regulate their expression have critical functions during normal development. A new study… 
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