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Protein Kinase M

 
National Institutes of Health

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Protein Kinase C

Papers overview

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Highly Cited
2015
Highly Cited
2015
Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis.
Long-term potentiation (LTP) of synaptic strength between hippocampal neurons is associated with learning and memory, and LTP… Expand
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Highly Cited
2013
Highly Cited
2013
PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory
Long-term potentiation (LTP), a well-characterized form of synaptic plasticity, has long been postulated as a cellular correlate… Expand
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Highly Cited
2013
Highly Cited
2013
Prkcz null mice show normal learning and memory
Protein kinase M-ζ (PKM-ζ) is a constitutively active form of atypical protein kinase C that is exclusively expressed in the… Expand
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Review
2011
Review
2011
How does PKMζ maintain long-term memory?
  • T. Sacktor
  • Nature Reviews Neuroscience
  • 2011
    • Corpus ID: 15231051
Most of the molecular mechanisms contributing to long-term memory have been found to consolidate information within a brief time… Expand
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Highly Cited
2011
Highly Cited
2011
Enhancement of Consolidated Long-Term Memory by Overexpression of Protein Kinase Mζ in the Neocortex
In rats, overexpression of a persistently active protein kinase C isoform enhances memories long after they have been formed… Expand
Highly Cited
2011
Highly Cited
2011
Protein Kinase M Maintains Long-Term Sensitization and Long-Term Facilitation in Aplysia
How the brain maintains long-term memories is one of the major outstanding questions in modern neuroscience. Evidence from… Expand
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Highly Cited
2011
Highly Cited
2011
Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase Mζ (PKMζ)
Activity-dependent synaptic plasticity is widely accepted to be the cellular correlate of learning and memory. It is believed… Expand
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Highly Cited
2010
Highly Cited
2010
PKMζ maintains memories by regulating GluR2-dependent AMPA receptor trafficking
The maintenance of long-term memory in hippocampus, neocortex and amygdala requires the persistent action of the atypical protein… Expand
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Highly Cited
2009
Highly Cited
2009
The atypical protein kinase C in Aplysia can form a protein kinase M by cleavage
In vertebrates, a brain‐specific transcript from the atypical protein kinase C (PKC) ζ gene encodes protein kinase M (PKM) ζ, a… Expand
1990
1990
Gangliosides Prevent Ischemia‐Induced Down‐Regulation of Protein Kinase C in Fetal Rat Brain
Abstract: Complete obstruction of the maternal blood flow to fetal rats at 20 days of gestation for a period of 10 min causes a… Expand
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