Protective Agents

Known as: protectant, protectants, Protective Drug 
A class of agents used in prophylactic or curative therapy to attenuate the negative side effects of toxins or drugs. Protective agents belong to… (More)
National Institutes of Health

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Papers overview

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Highly Cited
2007
Highly Cited
2007
Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin's disease.
PURPOSE Pediatric Oncology Group (POG) studies 9426 and 9425 evaluated dexrazoxane (DRZ) as a cardiopulmonary protectant during… (More)
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Review
2005
Review
2005
Bioactivity and protective effects of natural carotenoids.
Carotenoids comprise a class of natural fat-soluble pigments which are found in numerous fruits and vegetables. The consumption… (More)
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Review
2005
Review
2005
Nephron number, hypertension, renal disease, and renal failure.
Wendy E. Hoy,* Michael D. Hughson, John F. Bertram, Rebecca Douglas-Denton, and Kerstin Amann *Centre for Chronic Disease… (More)
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Highly Cited
2004
Highly Cited
2004
Selenium – an antioxidative protectant in soybean during senescence
Selenium (Se) is regarded as an antioxidant in animals and plants, even though considered as non-essential element in plants. To… (More)
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Review
2001
Review
2001
Protective role of probiotics and prebiotics in colon cancer.
Ingestion of viable probiotics or prebiotics is associated with anticarcinogenic effects, one mechanism of which is the… (More)
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Highly Cited
2001
Highly Cited
2001
Deep hypothermic circulatory arrest: I. Effects of cooling on electroencephalogram and evoked potentials.
BACKGROUND Deep hypothermia is an important cerebral protectant and is critical in procedures requiring circulatory arrest. The… (More)
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Highly Cited
2000
Highly Cited
2000
Effect of protective agents against cisplatin ototoxicity.
HYPOTHESIS The goals of this investigation were to compare the efficacy of three protective agents against cisplatin-induced… (More)
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Highly Cited
1997
Highly Cited
1997
THE OXIDATIVE BURST IN PLANT DISEASE RESISTANCE.
Rapid generation of superoxide and accumulation of H2O2 is a characteristic early feature of the hypersensitive response… (More)
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Highly Cited
1996
Highly Cited
1996
Calcium-mediated apoptosis in a plant hypersensitive disease resistance response
BACKGROUND Avirulent pathogens elicit a battery of plant defenses, often accompanied by collapse of the challenged cells. In… (More)
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Highly Cited
1996
Highly Cited
1996
Cryopreservation of human ovarian tissue using dimethylsulphoxide and propanediol-sucrose as cryoprotectants.
Pieces of ovarian cortical tissue (0.3-2 mm in diameter) were obtained during gynaecological operations by biopsy or as a result… (More)
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