Proteasome Inhibitors [MoA]

Known as: Proteasome Inhibitor, Proteasome Inhibitors, Proteosome Inhibitors 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
024619972016

Papers overview

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Review
2015
Review
2015
Proteasome inhibitors are indispensable research tools in immunology and cell biology. With numerous proteasome inhibitors… (More)
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2014
2014
Suberoyl bis-hydroxamic acid (SBHA) is a histone deacetylase (HDAC) inhibitor and exerts anti-growth effects in several… (More)
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2012
2012
The proteasome inhibitor bortezomib has shown remarkable clinical success in the treatment of multiple myeloma. However, the… (More)
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Highly Cited
2009
Highly Cited
2009
Proteasome inhibitors are currently in the clinic or in clinical trials, but the mechanism of their anticancer activity is not… (More)
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2009
2009
HIV-1 has proved to be notoriously difficult to tackle despite the availability of more than 20 clinically approved drugs. The… (More)
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Highly Cited
2008
Highly Cited
2008
Overexpression of antiapoptotic members of the Bcl-2 family is observed in approximately 80% of B-cell lymphomas, contributing to… (More)
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2008
2008
Proteasome inhibitors are emerging as effective drugs for the treatment of relapsed/refractory multiple myeloma and possibly some… (More)
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2006
2006
We have recently observed activation of wild-type (wt) p53 protein in human MCF-7 breast cancer cells upon treatment with… (More)
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2005
2005
Numerous signaling pathways were reported to be involved in the resistance for conventional cytotoxic drugs, although one of the… (More)
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2003
2003
Recently, we like others, demonstrated that systemic inflammation is the most important mechanism involved in (re)activation of… (More)
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